MENU

研究活動

論文（2016）

英文

原著論文

  1. Y. Yi, H. -J. Kim, P. Mi, M. Zheng, H. Takemoto, K. Toh, B. -S. Kim, K. Hayashi, M. Naito, Y. Matsumoto, K. Miyata, K. Kataoka, Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles. J. Control. Release 244 PartB 247-256 (2016) (DOI: 10.1016/j.jconrel.2016.08.041)
    The 14th edition of the European Symposium on Controlled Drug Delivery, Egmond aan Zee, The Netherlands on April 13-15, 2016
  2. N. Sasaki, M. Tatanou, T. Suzuki, Y. Anraku, A. Kishimura, K. Kataoka, K. Sato, A membrane-integrated microfluidic device to study permeation of nanoparticles through straight micropores toward rational design of nanomedicines. Anal. Sci. 32 (12) 1307-1314 (2016) (DOI: 10.2116/analsci.32.1307)
  3. K. Katsushima, A. Natsume, F. Ohta, K. Shinjo, A. Hatanaka, N. Ichimura, S. Sato, S. Takahashi, H. Kimura, Y. Totoki, T. Shibata, M. Naito, H. -J. Kim, K. Miyata, K. Kataoka, Y. Kondo, Targeting the notch-regulated non-coding RNA TUG1 for glioma treatment. Nat. Commun. 7 13616 (2016) (DOI: 10.1038/ncomms13616)
  4. Q. Chen, K. Osada, Z. Ge, S. Uchida, T. A. Tockary, A. Dirisala, A. Matsui, K. Toh, K. M. Takeda, X. Liu, T. Nomoto, T. Ishii, M. Oba, Y. Matsumoto, K. Kataoka, Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting. Biomaterials 113 253-265 (2016) (DOI: 10.1016/j.biomaterials.2016.10.042)
  5. S. Kikuta, Y. Matsumoto, A. Kuboki, T. Nakayama, D. Asaka, N. Otori, H. Kojima, T. Sakamoto, A. Kashio, K. Kanaya, R. Ueha, R. Kagoya, H. Nishijima, M. Toma-Hirano, Y. Kikkawa, K. Kondo, K. Tsunoda, T. Miyaji, T. Yamaguchi, K. Kataoka, K. Mori, T. Yamasoba, Longer latency of sensory response to intravenous odor injection predicts olfactory neural disorder. Sci. Rep. 6 35361 (2016) (DOI: 10.1038/srep35361)
  6. S. Uchida, K. Hayakawa, T. Ogata, S. Tanaka, K. Kataoka, K. Itaka, Treatment of spinal cord injury by an advanced cell transplantation technology using brain-derived neurotrophic factor-transfected mesenchymal stem cell spheroids. Biomaterials 109 1-11 (2016) (DOI: 10.1016/j.biomaterials.2016.09.007)
  7. Y. Takeuchi, N. Yahagi, Y. Aita, Y. Murayama, Y. Sawada, X. Piao, N. Toya, Y. Oya, A. Shikama, A. Takarada, Y. Masuda, M. Nishi, M. Kubota, Y. Izumida, T. Yamamoto, M. Sekiya, T. Matsuzaka, Y. Nakagawa, O. Urayama, Y. Kawakami, Y. Iizuka, T. Gotoda, K. Itaka, K. Kataoka, R. Nagai, T. Kadowaki, N. Yamada, Y. Lu, M. K. Jain, H. Shimano, KLF15 enables rapid switching between lipogenesis and gluconeogenesis during fasting. Cell Rep. 16 (9) 2373-2386 (2016) (DOI: 10.1016/j.celrep.2016.07.069)
  8. C.-Y. Lin, F. Perche, M. Ikegami, S. Uchida, K. Kataoka, K. Itaka, Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles. J. Control. Release 235 268-275 (2016) (DOI: 10.1016/j.jconrel.2016.06.001)
  9. P. Mi, D. Kokuryo, H. Cabral, H. Wu, Y. Terada, T. Saga, I. Aoki, N. Nishiyama, K. Kataoka, A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy. Nat. Nanotechnol. 11 (8) 724-730 (2016) (DOI: 10.1038/nnano.2016.72)
  10. R. N. Gilbreth, S. Novarra, L. Wetzel, S. Florinas, H. Cabral, K. Kataoka, J. RiosDoria, R. J. Christie, M. Baca, Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors. J. Control. Release 234 104-114 (2016) (DOI: 10.1016/j.jconrel.2016.05.041)
  11. H. Kinoh, Y. Miura, T. Chida, X. Liu, K. Mizuno, S. Fukushima, Y. Morodomi, N. Nishiyama, H. Cabral, K. Kataoka, Nanomedicines eradicating cancer stem-like cells in vivo by pH-triggered intracellular cooperative action of loaded drugs. ACS Nano 10 (6) 5643-5655 (2016) (DOI: 10.1021/acsnano.6b00900)

  12. T. Shirasu, H. Koyama, Y. Miura, K. Hoshina, K. Kataoka, T. Watanabe, Nanoparticles effectively target rapamycin delivery to sites of experimental aortic aneurysm in rats. PLOS ONE 11(6) e0157813 (2016) (DOI: 10.1371/journal.pone.0157813)
  13. H. Nishida, Y. Matsumoto, K. Kawana, R. J. Christie, M. Naito, B. -S. Kim, K. Toh, H. -S. Min, Y. Yi, Y. Matsumoto, H. -J. Kim, K. Miyata, A. Taguchi, K. Tomio, A. Yamashita, T. Inoue, H. Nakamura, A. Fujimoto, M. Sato, M. Yoshida, K. Adachi, T. Arimoto, O. Wada-Hiraike, K. Oda, T. Nagamatsu, N. Nishiyama, K. Kataoka, Y. Osuga, T. Fujii, Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes. J. Control. Release 231 29-37 (2016) (DOI: 10.1016/j.jconrel.2016.03.016)
  14. Y. Matsumoto, Y. Miyamoto, H. Cabral, Y. Matsumoto, K. Nagasaka, S. Nakagawa, D. Maeda, T. Yano, K. Oda, K. Kawana, N. Nishiyama, K. Kataoka, T. Fujii, Enhanced efficacy against cervical carcinomas through polymeric micelles physically incorporating the proteasome inhibitor MG132. Cancer Sci. 107 (6) 773-781
  15. Y. Matsumoto, J. W. Nichols, K. Toh, T. Nomoto, H. Cabral, Y. Miura, R. J. Christie, N. Yamada, T. Ogura, M. R. Kano, Y. Matsumura, N. Nishiyama, T. Yamasoba, Y. -H. Bae, K. Kataoka, Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery. Nat. Nanotechnol. 11 (6) 533-538 (2016) (DOI: 10.1038/nnano.2015.342)
    ・Drug delivery: Redefining tumour vascular barriers
  16. R. Taniguchi, Y. Miura, H. Koyama, T. Chida, Y. Anraku, A. Kishimura, K. Shigematsu, K. Kataoka, T. Watanabe, Adequately-sized nanocarriers allow sustained targeted drug delivery to neointimal lesions in rat arteries. Mol. Pharmaceutics 13 (6) 2108-2116 (2016) (DOI: 10.1021/acs.molpharmaceut.6b00219)
  17. F. Perche, Y. Yi, L. Hespel, P. Mi, A. Dirisala, H. Cabral, K. Miyata, K. Kataoka, Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity. Biomaterials 90 62-71 (2016) (DOI: 10.1016/j.biomaterials.2016.02.027)
  18. M. Wang, Y. Miura, K. Tsuchihashi, K. Miyano, O. Nagano, M. Yoshikawa, A. Tanabe, J. Makino, Y. Mochida, N. Nishiyama, H. Saya, H. Cabral, K. Kataoka, Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines. J. Control. Release 230 26-33 (2016) (DOI: 10.1016/j.jconrel.2016.03.038)
  19. H. Hino, M. Kamiya, K. Kitano, K. Mizuno, S. Tanaka, N. Nishiyama, K. Kataoka, Y. Urano, J. Nakajima, Rapid cancer fluorescence imaging using a γ-glutamyltranspeptidase-specific probe for primary lung cancer. Translational Oncology 9 (3) 203-210 (2016) (DOI: 10.1016/j.tranon.2016.03.007)
  20. S. Florinas, M. Liu, R. Fleming, L. V. V.-Ysla, J. Ayriss, R. Gilbreth, N. Dimasi, C. Gao, H. Wu, Z.-Q. Xu, S. Chen, A. Dirisala, K. Kataoka, H. Cabral, R. J. Christie, A Nanoparticle platform to evaluate bioconjugation and receptor-mediated cell uptake using crosslinked polyion complex micelles bearing antibody fragments. Biomacromolecules 17 (5) 1818-1833 (2016) (DOI: 10.1021/acs.biomac.6b00239)
  21. T. Nomoto, S. Fukushima, M. Kumagai, K. Miyazaki, A. Inoue, P. Mi, Y. Maeda, K. Toh, Y. Matsumoto, Y. Morimoto, A. Kishimura, N. Nishiyama, K. Kataoka, Calcium phosphate-based organic-inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy. Biomater. Sci. 4 (5) 826-838 (2016) (DOI: 10.1039/C6BM00011H)
  22. D. L. Stirland, Y. Matsumoto, K. Toh, K. Kataoka, Y. -H. Bae, Analyzing spatiotemporal distribution of uniquely fluorescent nanoparticles in xenograft tumors. J. Control. Release 227 38-44 (2016) (DOI: 10.1016/j.jconrel.2016.02.016)
  23. N. Dewi, P. Mi, H. Yanagie, Y. Sakurai, Y. Morishita, M. Yanagawa, T. Nakagawa, A. Shinohara, T. Matsukawa, K. Yokoyama, H. Cabral, M. Suzuki, Y. Sakurai, H. Tanaka, K. Ono, N. Nishiyama, K. Kataoka, H. Takahashi, In vivo evaluation of neutron capture therapy effectivity using calcium phosphate-based nanoparticles as Gd-DTPA delivery agent. J. Cancer Res. Clin. Oncol. 142 (4) 767-775 (2016) (DOI: 10.1007/s00432-015-2085-0)
  24. K. Hayashi, H. Chaya, S. Fukushima, S. Watanabe, H. Takemoto, K. Osada, N. Nishiyama, K. Miyata, K. Kataoka, Influence of RNA strand rigidity on polyion complex formation with block catiomers. Macromol. Rapid Commun. 37 (6) 486-493 (2016) (DOI: 10.1002/marc.201500661)
  25. S. Uchida, H. Kinoh, T. Ishii, A. Matsui, T. A. Tockary, K. M. Takeda, H. Uchida, K. Osada, K. Itaka, K. Kataoka, Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety. Biomaterials 82 221-228 (2016) (DOI: 10.1016/j.biomaterials.2015.12.031)
  26. T. A. Tockary, K. Osada, Y. Motoda, S. Hiki, Q. Chen, K. M. Takeda, A. Dirisala, S. Osawa, K. Kataoka, Rod-to-globule transition of pDNA/PEG-Poly(L-lysine) polyplex micelles induced by a collapsed balance between DNA rigidity and PEG crowdedness. Small 12 9 1193-1200 (2016) (DOI: 10.1002/smll.201501815)
  27. H. Hosoya, A. S. Dobroff, W. H. P. Driessen, V. Cristini, L. M. Brinker, F. I. Staquicini, M. C.-Vila, S. D’Angelo, F. Ferrara, B. Proneth, Y.-S. Lin, D. R. Dunphy, P. Dogra, M. P. Melancon, R. J. Stafford, K. Miyazono, J. G. Gelovani, K. Kataoka, C. J. Brinker, R. L. Sidman, W. Arap, R. Pasqualini, Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release. Proc. Natl. Acad. Sci. USA. 113 7 1877-1882 (2016) (DOI: 10.1073/pnas.1525796113)
  28. H. Uchida, K. Itaka, S. Uchida, T. Ishii, T. Suma, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka, Synthetic polyamines to regulate mRNA translation through the preservative binding of eukaryotic initiation factor 4E to the cap structure. J. Am. Chem. Soc. 138 (5) 1478-1481 (2016) (DOI: 10.1021/jacs.5b11726)
  29. A. Kim, Y. Miura, T. Ishii, O. F. Mutaf, N. Nishiyama, H. Cabral, K. Kataoka, Intracellular delivery of charge-converted monoclonal antibodies by combinatorial design of block/homo polyion complex micelles. Biomacromolecules 17 (2) 446-453 (2016) (DOI: 10.1021/acs.biomac.5b01335)
  30. T. Ishii, K. Miyata, Y. Anraku, M. Naito, Y. Yi, T. Jinbo, S. Takae, Y. Fukusato, M. Hori, K. Osada, K. Kataoka, Enhanced target recognition of nanoparticles by cocktail PEGylation with chains of varying lengths. Chem. Commun. 52 (7) 1517-1519 (2016) (DOI: 10.1039/C5CC06661A)
  31. Y. Anraku, A. Kishimura, M. Kamiya, S. Tanaka, T. Nomoto, K. Toh, Y. Matsumoto, S. Fukushima, D. Sueyoshi, M. R. Kano, Y. Urano, N. Nishiyama, K. Kataoka, Systemically injectable enzyme-loaded polyion complex vesicles as in vivo nanoreactors functioning in tumors. Angew. Chem. Int. Ed. 128 (2) 570-575 (2016) (DOI: 10.1002/ange.201508339)
  32. S. Osawa, K. Osada, S. Hiki, A. Dirisala, T. Ishii, K. Kataoka, Polyplex micelles with double-protective compartments of hydrophilic shell and thermo-switchable palisade of poly(oxazoline)-based block copolymers for promoted gene transfection. Biomacromolecules 17 (1) 354-361 (2016) (DOI: 10.1021/acs.biomac.5b01456)
  33. M. Tangsangasaksri, H. Takemoto, M. Naito, Y. Maeda, D. Sueyoshi, H. -J. Kim, Y. Miura, J. -Y. Ahn, R. Azuma, N. Nishiyama, K. Miyata, K. Kataoka, siRNA-loaded polyion complex micelle decorated with charge-conversional polymer tuned to undergo stepwise response to intra-tumoral and intra-endosomal pHs for exerting enhanced RNAi efficacy. Biomacromolecules 17 (1) 246-255 (2016) (DOI: 10.1021/acs.biomac.5b01334)
  34. H. Aini, K. Itaka, A. Fujisawa, H. Uchida, S. Uchida, S. Fukushima, K. Kataoka, T. Saito, U. -I. Chung, S. Ohba, Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment. Sci. Rep. 6 18743 (2016) (DOI: 10.1038/srep18743)
  35. A. Nagaoka, H. Takehara, A. Hayashi-Takagi, J. Noguchi, K. Ishii, F. Shirai, S. Yagishita, T. Akagi, T. Ichiki, H. Kasai, Abnormal intrinsic dynamics of dendritic spines in a fragile X syndrome mouse model in vivo. Sci. Rep. 6 26651 (2016) (DOI: 10.1038/srep26651)

総説

  1. H. -J. Kim, A. Kim, K. Miyata, K. Kataoka, Recent progress in development of siRNA delivery vehicles for cancer therapy. Adv. Drug Deliv. Rev. 104 61-77 (2016) (DOI: 10.1016/j.addr.2016.06.011)
  2. N. Nishiyama, Y. Matsumura, K. Kataoka, Development of polymeric micelles for targeting intractable cancers. Cancer Sci. 107 (7) 867-874 (2016) (DOI: 10.1111/cas.12960)

和文

総説

  1. 宮田完二郎、長田健介、片岡一則 PEG-ポリアミノ酸ブロック共重合体の自己組織化体：高分子ミセル型DDS Drug Delivery System 31 (4) 283-292 (2016)
  2. 加藤くみ子、石原比呂之、友田寛、松田嘉弘、永井尚美、花田博幸、久田茂、小野寺博志、西山伸宏、原島秀吉、松村保広、片岡一則、合田幸広、奥田晴宏、川西徹 リポソーム製剤の特性と評価 医薬品医療機器レギュラトリーサイエンス 47 (5) 333-341 (2016)
  3. 宮田完二郎、内田智士、内藤瑞、片岡一則 高分子ナノテクノロジーが切り拓く核酸医薬デリバリー Drug Delivery System 31 (1) 44-53 (2016)

著書

  1. 内田智士、位髙啓史、片岡一則 高分子ナノミセルを用いた生体へのin vivo mRNAデリバリー トランスレーショナルリサーチを支援する遺伝子医学MOOK30号 今、着実に実り始めた遺伝子治療－最新研究と今後の展開 金田安史 編 株式会社メディカルドゥ 大阪 (2016)
  2. 宮田完二郎、片岡一則 第III編 DDS 第2章 高分子集合体に基づく核酸デリバリーシステム 核酸医薬の創製と応用展開 和田猛 監修 シーエムシー出版 東京 (2016) 175-184