[Original paper / Review]   [Misc.]   [Press/magazine]

Original paper / Review (2015~)

    1. N. Seo and T. Ichiki, “Negative Surface Charge and Membrane Lipid Composition Underlying Extracellular Vesicle Function”, ACS Nano Medicine, (2026).
      doi: 10.1021/acsnanomed.5c00108
    2. S. Ueno , F. Toshioka , T. Ichiki, “PL-display: A cell-free platform for tunable selection of affinity peptides”, PNAS Nexus, pgag031(2026).
      doi: 10.1093/pnasnexus/pgag031
    3. S. Kawakami, R. Sato, H. Ejima, T. Ujii, K. Sato, T. Ichiki, Yasushi Shibuta, “Molecular Dynamics Study of Polymer Coiling in a Water−Organic Binary Solvent System”, ACS Omega (2025).
      doi: 10.1021/acsomega.5c05389
    4. M. Fukuhara, H. Takehara, H. Hidaka, K. Barthelmes, B. Kersch-Hunt, J. E. Gardiner, Y. Kanda, A. Matsumoto, T. D. James, T. Ichiki, “Development of an optical microneedle device embedding sub-nanoliter volumes of boronic acid-based fluorescent hydrogel”, J. Mater. Chem. B, (2025).
      doi: 10.1039/D5TB00385G
    5. Y. Kanda, H. Takehara and T. Ichiki, ” Modeling of elastoplastic deformation of polymeric microneedles using finite element method”, J. Photopolymer Sci. Technol. 38(4), 291-294 (2025). doi: 10.2494/photopolymer.38.291
    6. Q. Kang, H. Takehara, T. Ichiki, “Comparative study of piezoelectric properties in electrospun PLLA and PVDF nanofibers: Influence of crystallinity and molecular orientation”, Polym. Test., 151, 108958 (2025).
      doi: 10.1016/j.polymertesting.2025.108958
    7. C. Wang, A. Fulati, K. Kimura, X. Li, J.J. Richardson, M. Naito, K. Miyata, T. Ichiki, H. Ejima, “Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal-Phenolic Networks”, Advanced healthcare materials, e2405188 (2025).
      doi: 10.1002/adhm.202405188
    8. H. Takehara, M. Inada, Y. Kanda, T. Ichiki, “Mechanical finite element analysis of needle tip shape to develop insertable polymer-based microneedle without plastic deformation”, J. Mech. Behav. Biomed. Mater. 163, 106885 (2025).
      doi: 10.1016/j.jmbbm.2025.106885
    9. R. Sato, S. Kawakami, H. Ejima, T. Ujii, T. Ichiki, Y. Shibuta, “Dynamic correlation analysis between stress–strain curve and polymer film structure using persistent homology”, J. Chem. Theory Comput. 20(24), 10798–10806 (2024).
      doi: 10.1021/acs.jctc.4c01418
    10. Y. Takakura, R. Hanayama, K. Akiyoshi, S. Futaki, K. Hida, T. Ichiki, A. Ishii-Watanabe, M. Kuroda, K. Maki, Y. Miura, Y. Okada, N. Seo, T. Takeuchi, T. Yamaguchi and Y. Yoshioka, “Quality and Safety Considerations for Therapeutic Products Based on Extracellular Vesicles”, Pharm. Res. 41(8), 1573-1594 (2024).
      doi: 10.1007/s11095-024-03757-4
    11. M. Fukuhara, H. Takehara, Y. Kanda, and T. Ichiki, “Functionalization of Poly-L-Lactic Acid Microneedle Tips using Hydrogel Photopolymerization”, J. Photopolymer Sci. Technol. 37(2), 233-237 (2024).
      doi: 10.2494/photopolymer.37.233
    12. Y. Kanda, H. Kuramochi, H. Takehara and T. Ichiki, “Effects of Solvents on the Preparation of PLLA/PEDOT: PSS Conductive Polymer Alloy Films”, J. Photopolymer Sci. Technol. 37(2), 239-244 (2024).
      doi: 10.2494/photopolymer.37.239
    13. Q. Kang, H. Takehara, T. Ichiki, “Effect of pH on the properties of protonated polyaniline-based films for pH sensing applications”, J. Appl. Polymer Sci. e55110 (2024).
      doi: 10.1002/app.55110
    14. H. Suzuki, H. Ejima, I. Ohnishi, T. Ichiki, Y. Shibuta, “Molecular dynamics simulation of adhesion of additive molecules in paint materials toward enhancement of anticorrosion performance”, ACS Omega 9(4), pp. 4656-4663 (2024)
      doi: 10.1021/acsomega.3c07902
    15. H. Fukuda, H. Kuramochi, Y. Shibuta, T. Ichiki, “Analysis of Brownian motion trajectories of non-spherical nanoparticles using deep learning”, APL mach. learn. 1(4) 046104 (2023).
      doi: 10.1063/5.0160979
    16. Q. Kang, H. Takehara, T. Ichiki, “Characterization of the electrical conductivity and chemical properties of camphorsulfonic acid protonated polyaniline/poly(vinyl acetate) composite films”, Polymer 283, 126269 (2023).
      doi: 10.1016/j.polymer.2023.126269
    17. Q. Kang, H. Takehara, T. Ichiki, “A polyaniline/polyvinyl acetate composite film electrode for highly sensitive electrochemical sensing of pH”, Synth. Met. 297, 117380 (2023).
      doi: 10.1016/j.synthmet.2023.117380
    18. Y. Kanda, H. Takehara, T. Ichiki, “Optical oxygen measurement using microneedle of bioabsorable polymer”, J. Photopolymer Sci. Technol. 36(1), 15-18 (2023).
      doi: 10.2494/photopolymer.36.15
    19. 倉持 宏実、一木 隆範「生体ナノ粒子の1粒子分析・層別化技術」、SoftMatter 60, pp.10-12 (2023)
    20. K. Takizawa, K. Ueda, M. Sekiguchi, E. Nakano, T. Nishimura, Y. Kajiho, S. Kanda, K. Miura, M. Hattori, J. Hashimoto, Y. Hamasaki, M. Hisano, T. Omori, T. Okamoto, H. Kitayama, N. Fujita, H. Kuramochi, T. Ichiki, A. Oka, Y. Harita, “Urinary extracellular vesicles signature for diagnosis of kidney disease”, iScience 25(11) 105416 (2022).
      doi: 10.1016/j.isci.2022.105416
    21. A. Kahn, Y. Hadano, H. Takehara, and T. Ichiki, “Effects of physico-chemical treatments on PLGA 50:50 electrospun nanofibers”, Polymer 261, 125400 (2022).
      doi: 10.1016/j.polymer.2022.125400
    22. Y. Kanda, H. Takehara, and T. Ichiki, “Experimental and numerical studies of deformation of truncated-cone-shaped poly (L-lactic acid) microneedle during insertion”, Appl. Phys. Express 15, 106503 (2022).
      doi: 10.35848/1882-0786/ac9453
    23. N. Seo, J. Nakamura,T. Kaneda, H. Tateno, A. Shimoda, T. Ichiki, K. Furukawa, J. Hirabayashi, K. Akiyoshi, and H. Shiku, “Distinguishing functional exosomes and other extracellular vesicles as a nucleic acid cargo by the anion-exchange method”, J. Extracellular Vesicles 11, Issue 3, e12205 (2022).
      doi: 10.1002/jev2.12205
    24. S. S. Koyagura, H. Takehara and T. Ichiki, “Experimental evaluation and modeling of adsorption phenomena of nanoliposomes on poly(dimethylsiloxane) surfaces”, J. Photopolymer Sci. Technol. 34(1), 1-5 (2021).
      doi: 10.2494/photopolymer.34.1
    25. C. Wang, K. Kimura, J. Li, J. J. Richardson, M. Naito, K. Miyata, T. Ichiki, H. Ejima, Polydopamine-mediated surface functionalization of exosomes. ChemNanoMat 7, 592–595 (2021).
      doi: 10.1002/cnma.202100078
    26. 一木隆範、「細胞外小胞の1粒子分析・層別化技術」、Drug Delivery System 36(2), pp.117-123 (2021).
      doi: 10.2745/dds.36.117
    27. 竹原宏明、内藤孝太、一木隆範、生分解性エレクトロニクスのためのポリ-L-乳酸製基板の表面処理とモリブデン電極形成 IEEJ Trans. SM 141(3) 88-89 (2021)
      doi: 10.1541/ieejsmas.141.88
    28. B.S. Kim, M. Naito, R. Kamegawa, H.J. Kim, R. Iizuka, T. Funatsu, S. Ueno, T. Ichiki, A. Kishimura, and K. Miyata,
      “Photo-reactive oligodeoxynucleotide-embedded nanovesicles (PROsomes) with switchable stability for efficient cellular uptake and gene knockdown”,
      Chem. Commun. 56, 9477-9480 (2020).
      doi: 10.1039/D0CC01750G
    29. S. Saito, H. Takehara, and T. Ichiki,
      “Electrospray using an ionic liquid counter electrode and its characterization by the spray current measurement”,
      J. Photopolymer Sci. Technol. 33, 337-341 (2020).
      doi: 10.2494/photopolymer.33.337
    30. S.S. Koyagura, H. Takehara, and T. Ichiki,
      “Chemical etching treatment of polydimethylsiloxane for smoothing microchannel surface”,
      J. Photopolymer Sci. Technol. 33, 485-490 (2020).
      doi: 10.2494/photopolymer.33.485
    31. V. Majarikar, H. Takehara, T. Ichiki,
      “Optical measurement platform of temperature-dependent interaction between nanoliposomes and a polymer-grafted surface”,
      Biomed. Microdevices 22, 33 (2020).
      doi: 10.1007/s10544-020-00489-1
    32. H. Takehara, Y. Hadano, Y. Kanda, and T. Ichiki,
      “Effect of the thermal history on the crystallinity of poly (L-lactic acid) during the micromolding process”,
      Micromachines 11, 452 (2020).
      doi: 10.3390/mi11050452
    33. Y. Kuwahata, H. Takehara, and T. Ichiki,
      “Comprehensive study on electrospray deposition in the single Taylor cone-jet mode by changing the spatial electric potential using a ring-shaped ternary electrode”,
      AIP Advances 10, 045107 (2020).
      doi: 10.1063/1.5142317
    34. S. Sato, S. Ueno, and T. Ichiki,
      “A surface modification process for silica microreactor array chips to seal aqueous solutions”,
      Jpn. J. Appl. Phys. 59, SIIK01 (2020).
      doi: 10.35848/1347-4065/ab7adf
    35. S. Yokota, H. Kuramochi,K. Okubo, A. Iwaya, S. Tsuchiya and T. Ichiki,
      “Extracellular vesicles nanoarray technology: Immobilization of individual extracellular vesicles on nanopatterned polyethylene glycol-lipid conjugate brushes”,
      PLOS ONE 14, e0224091 (2019).
      doi: 10.1371/journal.pone.0224091
    36. H. Takehara, S. Sato, and T. Ichiki,
      “All-polymer-based micro free-flow electrophoresis (μFFE) device with cellulose permeable membranes”,
      Appl. Phys. Express 12, 107001 (2019).
      doi: 10.7567/1882-0786/ab3d64
    37. V. Majarikar, H. Takehara, and T. Ichiki,
      “Adsorption phenomena of anionic and cationic nanoliposomes on the surface of poly(dimethylsiloxane) microchannel”,
      J. Photopolymer Sci. Technol. 32, 107-113 (2019).
      doi: 10.2494/photopolymer.32.107
    38. K. Hashimoto, H. Takehara, and T. Ichiki,
      “Plasma-assisted electrospray deposition of thin elastomer films”,
      Jpn. J. Appl. Phys. 58, SDDK04 (2019).
      doi: 10.7567/1347-4065/ab0ff7
    39. Y. Kanda, H. Takehara, and T. Ichiki,
      “Mechanical strength evaluation of crystalline poly (L-lactic acid) fabricated by replica micromolding for bioabsorbable microneedle devices”,
      Jpn. J. Appl. Phys. 58, SDDK05 (2019).
      doi: 10.7567/1347-4065/ab0ff6
    40. T. Rahman, T. Masui, and T. Ichiki,
      “Electrical characterization of electrolyte/β- Ga2O3 junction for biosensing applications”,
      J. Electrochem. Soc. 166, B414-B420 (2019).
      doi: 10.1149/2.0501906jes
    41. S. Matsumura, T. Minamisawa, K. Suga, H. Kishita, T. Akagi, T. Ichiki, Y. Ichikawa and K. Shiba,
      “Subtypes of tumor cell-derived small extracellular vesicles having differently externalized phosphatidylserine”,
      J. Extracellular Vesicles 8, 1579541 (2019).
      doi: 10.1080/20013078.2019.1579541
    42. T. Ono, T. Ichiki, H. Noji,
      “Digital enzyme assay using attoliter droplet array”,
      Analyst 143, 4923-1929 (2018).
      doi: 10.1039/C8AN01152D
    43. V. Majarikar, H. Takehara, T. Ichiki,
      “Microcapillary electrophoresis chip with a bypass channel for autonomous compensation of hydrostatic pressure flow”,
      Microfluidics and Nanofluidics 22, 110 (2018).
      doi: 10.1007/s10404-018-2134-5
    44. S. Ueno, M. Shioya, T. Ichiki,
      “Fluorometric measurement of adenosine 5′-triphosphate using exonuclease V activity”,
      J. Photopolymer Sci. Technol., (2018). (in press)
    45. H. Takehara, Y. Kanda, T. Ichiki,
      “Microfluidic model for optical detection of nanoparticles in whole blood”,
      J. Photopolymer Sci. Technol. 31, 59-63 (2018).
      doi: 10.2494/photopolymer.31.59
    46. Y. Okamoto, H. Takehara, K. Fujimoto, T. Ichiki, T. Ohba, Y. Mita,
      “On-chip high-voltage charge pump with MEMS post-processed standard 5-V CMOS on SOI for electroosmotic flow micropumps”,
      IEEE Electron Device Lett. 39, 851-854 (2018).
      doi: 10.1109/LED.2018.2829925
    47. T. Rahman, T. Ichiki,
      “Fabrication and characterization of a stabilized thin film Ag/AgCl reference electrode modified with self-assembled monolayer of alkane thiol chains for rapid biosensing applications”,
      Sensors 17, 2326 (2017).
      doi: 10.3390/s17102326
    48. S. Ueno, T. Ichiki,
      “Phototriggered control of enzyme reactions toward high-throughput screening on a microwell array chip”,
      J. Photopolymer Sci. Technol. 30, 657-660 (2017).
      doi: 10.2494/photopolymer.30.657
    49. T. Akagi, T. Ichiki,
      “Microcapillary Chip-Based Extracellular Vesicle Profiling System in Extracellular Vesicles”,
      Methods Mol. Biol. 1660, 209-217 (2017).
      doi: 10.1007/978-1-4939-7253-1_17
    50. K. Ishikawa, K. Karahashi, T. Ichiki, J. P. Chang, S. M. George, W. M. M. Kessels, H.-J. Lee, S. Tinck, J.-H. Um, K. Kinoshita,
      “Progress and prospects in nanoscale dry processes: How can we control atomic layer reactions?”,
      Jpn. J. Appl. Phys. 56, 06HA02 (2017).
      doi: 10.7567/JJAP.56.06HA02
    51. H. Takehara, A. Nagaoka, J. Noguchi, T. Akagi, H. Kasai, T. Ichiki,
      “Implantable microfluidic device with hydrogel permeable membrane for delivering chemical compounds and imaging neural cells in living mice”,
      J. Photopolymer Sci. Technol. 29, 513-518 (2016).
      doi: 10.2494/photopolymer.29.513
    52. A. Nagaoka, H. Takehara, A. Hayashi-Takagi, J. Noguchi, K. Ishii, F. Shirai, S. Yagishita, T. Akagi, T. Ichiki, H. Kasai,
      “Abnormal intrinsic dynamics of dendritic spines in a fragile X syndrome mouse model in vivo”,
      Scientific Reports 6, 26651 (2016).
      doi: 10.1038/srep266
    53. M. Kojima, H. Takehara, T. Akagi, H. Shiono, T. Ichiki,
      “Flexible sheet-type sensor devices for noninvasive measurement of cellular oxygen metabolism on a culture dish”,
      PLOS ONE 10, e0143774 (2015).
      doi: 10.1371/journal.pone.0143774
    54. 一木 隆範, 赤木 貴則,
      「ナノ医療を加速するナノ粒子解析プラットフォームの開発」,
      Drug Delivery System 30, 204-211 (2015).
      doi: 10.2745/dds.30.204
    55. M. Biyani, T. Ichiki,
      “Microintaglio printing for soft lithography-based in situ microarrays”,
      Microarrays 4, 311-323 (2015).
      doi: 10.3390/microarrays4030311
    56. S. Ueno, T. Hirai, S. Sato, M. Biyani, H. Kuramochi, R. Iizuka, T. Akagi, T. Funatsu, T. Ichiki,
      “In situ synthesis and immobilization of enzyme molecules on microreactor array chips”,
      J. Photopolymer Sci. Technol. 5, 719 -726 (2015).
      doi: 10.2494/photopolymer.28.719
    57. T. Akagi, N. Hanamura, T. Ichiki,
      “Measurement of individual nanobioparticles on microfluidic chips by laser dark-field imaging”,
      J. Photopolymer Sci. Technol. 5, 727-730 (2015).
      doi: 10.2494/photopolymer.28.727
    58. 上野 真吾, ビヤニ　マニッシュ, 佐藤 秀介, ラジ・クマール スバシニ, 倉持 宏実, 赤木 貴則, 一木 隆範,
      「高集積マイクロアレイ研究開発の現状と動向」,
      分析化学 64, 421-429 (2015).
      doi: 10.2116/bunsekikagaku.64.421
    59. T. Akagi, R. Kubota, M. Kobayashi, T. Ichiki,
      “Development of a polymer-based easy-to-fabricate micro-free-flow electrophoresis devices”,
      Jpn. J. Appl. Phys. 54, 06FN05 (2015).
      doi: 10.7567/JJAP.54.06FN05
    60. T. Akagi, K. Kato, M. Kobayashi, N. Kosaka, T. Ochiya, T. Ichiki,
      “On-chip immunoelectrohoresis of extracellular vesicles released from human breast cancer cells”,
      PLOS ONE 10, e0123603 (2015).
      doi: 10.1371/journal.pone.0123603
    61. C. Jiang, K. Uto, M. Ebara, T. Aoyagi, T. Ichiki,
      “Implementation of poly(ε-caprolactone) sheet-based shape-memory microvalves into plastic-based microfluidic devices”,
      Jpn. J. Appl. Phys. 54, 06FN02 (2015).
      doi: 10.7567/JJAP.54.06FN02
    62. Q. Chen, T. Ichiki,
      “80-mm-wide cold atmospheric-pressure plasma generated by two parallel but horizontally separated electrodes”,
      Plasma Source Science and Technology 24, 025022 (2015).
      doi: 10.1088/0963-0252/24/2/025022
    63. T. Rahman, T. Masui, T. Ichiki,
      “A single-crystal gallium oxide based biomolecular modified diode for nucleic acid sensing”,
      Jpn. J. Appl. Phys. 54, 04DL08 (2015).
      doi: 10.7567/JJAP.54.04DL08
    64. R. Kobayashi, M. Biyani, S. Ueno, S. R. Kumal, H. Kuramochi, T. Ichiki
      “Temperature-controlled microintaglio printing (TC-μIP) for high-resolution micropatterning of transcribed RNA molecules”
      Biosens. Bioelectron. 67, 115-120 (2015).
      doi: 10.1016/j.bios.2014.07.050

Misc. (2015~)

  1. 一木隆範
    第Ⅱ編 第1章 4. “分泌型miRNA診断デバイスの開発”
    『バイオチップの基礎と応用―原理から最新の研究・開発動向まで―』
    伊藤嘉浩 監修 シーエムシー出版（2015）53-59
  2. 上野真吾、一木隆範
    第Ⅱ編 第2章 3. “無細胞タンパク質合成系を利用したタンパク質マイクロアレイ”
    『バイオチップの基礎と応用―原理から最新の研究・開発動向まで―』
    伊藤嘉浩 監修 シーエムシー出版（2015）84-93

Press/magazine (2015~)