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Abbasi, Saed

Research contents (Research key words)

drug and nucleic acid delivery, gene editing, mRNA vaccines, lipid nanoparticles, polymeric micelles

Biography

 

Performance

1. Abbasi, S., Uchida, S., Toh, K., Tockary, T. A., Dirisala, A., Hayashi, K., Fukushima, S., & Kataoka, K. (2021). Co-encapsulation of Cas9 mRNA and guide RNA in polyplex micelles enables genome editing in mouse brain. Journal of Controlled Release, 332, 260–268.
2. Abbasi, S., Sato, Y., Kajimoto, K., & Harashima, H. (2020). New Design Strategies for Controlling the Rate of Hydrophobic Drug Release from Nanoemulsions in Blood Circulation. Molecular Pharmaceutics, 17(10), 3773–3782.
3. Dirisala, A., Uchida, S., Toh, K., Li, J., Osawa, S., Tockary, T. A., Liu, X., Abbasi, S., Hayashi, K., Mochida, Y., Fukushima, S., Kinoh, H., Osada, K., & Kataoka, K. (2020). Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines. Science Advances, 6(26), eabb8133.
4. Abbasi, S., Kajimoto, K., & Harashima, H. (2018). Critical parameters dictating efficiency of membrane-mediated drug transfer using nanoparticles. International Journal of Pharmaceutics, 553(1–2), 398–407.
5. Abbasi, S., Kajimoto, K., & Harashima, H. (2016). Elimination of the biphasic pharmacodynamics of 15d-PGJ2 by controlling its release from a nanoemulsion. International Journal of Nanomedicine, 2685.
6. El-Sabawi, D., Abbasi, S., Aljafari, S., Hamdan, I. (2013). Pharmaceutical evaluation of glibenclamide products available in the Jordanian market. Afr. J. Pharm. Pharmacol, 7: 1464-70

Affiliation Society

 

Patents pending

1. Solubilizing Agent (PCT/JP2021/005310)
2. Genome editing micelle (JP2020-113434)

Received grants

JSPS postdoctoral fellowship (April 2019 - April 2020)