Principal Research Scientist / Laboratory Head
Professor, Department of Materials Engineering, The University of Tokyo
Research contents (Research key words)
We are developing the innovative diagnostics device which is usable in any hospital/clinic and home. The device enable rapid (approx. 30 min) diagnosis of cancers from a small volume of specimen based on the detection of microRNA which have been attracting attention as a newly biomarker for cancer diagnosis.
We are also developing an original accurate analytical method of nano-particles such as exosome.
Keywords: Biodevice, Highly-integrated bio-microarray, Nano-diagnosis, microRNA, Exosome, Rapid molecular evolution
Ph.D. degree was received from The University of Tokyo.
Assistant Professor, Lecturer, and Associate Professor of the Department of Electric and Electronics Engineering, Toyo University, where LSI microfabrication technology and bioelectronics were studied.
Associate Professor of Department of Bioengineering, The University of Tokyo.
Project Associate Professor of Nano-BioSensing Social Cooperation Laboratory, The University of Tokyo.
Principal Research Scientist of Innovation Center of NanoMedicine (iCONM).
Professor of Department of Materials Engineering, The University of Tokyo.
- T. Akagi， K. Kato， M. Kobayashi， N. Kosaka， T. Ochiya， and T. Ichiki， “On-chip immunoelectrohoresis of extracellular vesicles released from human breast cancer cells”， PLOS ONE， 10， e0123603 (2015).
- R. Kobayashi， M. Biyani， S. Ueno， S. Raj Kumal， H. Kuramochi， and T. Ichiki， “Temperature-controlled microintaglio printing (TC-μIP) for high-resolution micropatterning of transcribed RNA molecules”， Biosensors and Bioelectronics 67, 115-120 (2015).
- H. Takehara， A. Nagaoka， J. Noguchi， T. Akagi， H. Kasai and T. Ichiki， “Lab-on-a-brain: Implantable micro-optical fluidic devices for neural cell analysis in vivo”， Scientific Reports， 4， Article number: 6721 (2014).
- M. Biyani， J. Moriyasu， Y. Tanaka， S. Sato， S. Ueno and T. Ichiki， “Microintaglio printing of in situ synthesized proteins enables rapid printing of high-density protein microarrays directly from DNA microarrays”， Appl. Phys. Express， 6， 087001 (2013).
- K. Kato， M. Koido， M. Kobayashi， T. Akagi， and T. Ichiki， “Statistical fluctuation in zeta potential distribution of nanoliposomes measured by on-chip microcapillary electrophoresis”， Electrophoresis， 34(8) pp. 1212-1218 (2013).
- H. Takehara， C.Y Jiang， K.Uto， M. Ebara， T. Aoyagi and T. Ichiki， “Novel microfluidic valve technology based on shape memory effect of poly(ε-caprolactone)”， Appl. Phys. Express， 6， 037201(2013).
- H. Takehara， A. Nagaoka， J. Noguchi， T. Akagi， T. Sakai， U.-I Chung， H. Kasai and T. Ichiki， “Implementation of tetra-poly(ethylene glycol) hydrogel with high mechanical strength into microfluidic device technology”， Biomicrofluidics， 7， 054109 (2013).
The Japan Society of Applied Physics, The Surface Finishing Society of Japan, Japanese Society of Extracellular Vesicles.