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Members

KANO,  Mitsunobu R

Biography

• 1999

  Graduated Faculty of Medicine, The University of Tokyo (MD)

• 2001 - 2005

  Graduate School of Medicine, The University of Tokyo (PhD. In 2005)

• 1999 – 2002

  Internal medicine Resident in in St. Luke’s International Hospital, Chief Resident (2002)

• 2002 – 2005

  Registered clinical doctor, The University of Tokyo Hospital

• 2005 – 2006

  Academic Research support, Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo

• 2006 – 2008

  Project Professor, Center for Nanobio Integration, The University of Tokyo

• 2008 – 2012

  Associate Professor, Medical Scientist Training Program, Faculty of Medicine, The University of Tokyo

• 2012 – 2017

  Professor, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University

• 2016 – 2017

  Deputy Dean (Concurrent appointment), Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University

• 2017 – 2018

  Vice Executive Director (Research), Okayama University

• 2018 – present

  Professor, Department of Pharmaceutical Biomedicine, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University

• 2018 – present

  Vice Executive Director (in charge of planning, evaluation and general affairs)・ Chairman, SDGs promotion planning meeting, Okayama University

• 2019 - present

  Science and Technology Co-Advisor to the Minister of Foreign Affairs
  https://www.mofa.go.jp/press/release/press4e_002434.html

Achievement

Original paper

• Paper: 76 (h-index: 35)
• Review: 7
• Series: 5

Major paper

1. Tanaka HY, Kano MR, et al. Heterotypic 3D pancreatic cancer model with tunable proportion of fibrotic elements. Biomaterials 2020;251:120077.
2. Tanaka HY, Kano MR, et al. Pancreatic stellate cells derived from human pancreatic cancer demonstrate aberrant SPARC-dependent ECM remodeling in 3D engineered fibrotic tissue of clinically relevant thickness. Biomaterials 2019;192:355-367.
3. Sakai S, Tanaka HY, Kano MR, et al. Increased fibrosis and impaired intratumoral accumulation of macromolecules in a murine model of pancreatic cancer co-administered with FGF-2. J Control Rel 2016; 230, 109-115.
4. Cabral H, Kano MR, et al. Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. Nat Nanotechnol 2011;6(12):815-23.
5. Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling. Proc Natl Acad Sci 2007;104(9), 3460-3465.

Award

1. DDS Encouragement Award (2014)
2. The University of Tokyo Faculty of Medicine Best Teacher’s Award (2012)
3. The Young Investigator Awards of the Japanese Cancer Association (2008)
4. Inoue Research Award for Young Scientists (2008)

And many others

Academic Society

• Science Council of Japan , member (2011 – present)
• The Japan Society of Drug Delivery System , Academic Councilor (2011 - present) Director (2018 - present)
• Japanese Cancer Association, Academic Councilor (2013 - present)