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Article FY 2012
| 1. | H. Hojo, S. Ohba, F. Yano, T. Saito, T. Ikeda, K. Nakajima, Y. Komiyama, N. Nakagata, K. Suzuki, T. Takato, H. Kawaguchi, U.-I. Chung, "Gli1 protein participates in the hedgehog-mediated specification of the osteoblast lineage during endochondral ossification", J. Biol. Chem., 287(21), 17860-17869, 2012. DOI: 10.1074/jbc.M112.347716 |
| 2. | Y. Song, M. Noguchi, K. Takatsuki, T. Sekiguchi, J. Mizuno, T. Funatsu, S. Shoji, M. Tsunoda, "Integration of pillar array columns into a gradient elution system for pressure-driven liquid chromatography", Anal. Chem., 84(11), 4739-4745, 2012. DOI: 10.1021/ac3001836 |
| 3. | M. Rafi, H. Cabral, M. R. Kano, P. Mi, C. Iwata, M. Yashiro, K. Hirakawa, K. Miyazono, N. Nishiyama, K. Kataoka, "Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis", J. Control. Release, 159(2), 189-196, 2012. DOI: 10.1016/j.jconrel.2012.01.038 |
| 4. | H. Hosoya, K. Kadowaki, M. Matsusaki, H. Cabral, H. Nishihara, H. Ijichi, K. Koike, K. Kataoka, K. Miyazono, M. Akashi, M. R. Kano, "Engineering fibrotic tissue in pancreatic cancer: a novel three-dimensional model to investigate nanoparticle delivery", Biochem. Biophys. Res. Commun., 419(1), 32-37, 2012. DOI: 10.1016/j.bbrc.2012.01.117 |
| 5. | K. Yamamoto, H. Hojo, I. Koshima, U.-I. Chung, S. Ohba, "Famotidine suppresses osteogenic differentiation of tendon cells in vitro and pathological calcification of tendon in vivo", J. Orthop. Res., 30(12), 1958-1962, 2012. DOI: 10.1002/jor.22146 |
| 6. | R. J. Christie, Y. Matsumoto, K. Miyata, T. Nomoto, S. Fukushima, K. Osada, J. Halnaut, F. Pittella, H.-J. Kim, N. Nishiyama, K. Kataoka, "Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection", ACS Nano, 6(6), 5174-5189, 2012. DOI: 10.1021/nn300942b |
| 7. | Q. Chen, K. Osada, T. Ishii, M. Oba, S. Uchida, T. A. Tockary, T. Endo, Z. Ge, H. Kinoh, M. R. Kano, K. Itaka, K. Kataoka, "Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic antiangiogenic gene therapy for fibrotic pancreatic tumors", Biomaterials, 33(18), 4722-4730, 2012. DOI: 10.1016/j.biomaterials.2012.03.017 |
| 8. | S. Uchida, K. Itaka, Q. Chen, K. Osada, T. Ishii, M. A. Shibata, M. Harada-Shiba, K. Kataoka, "PEGylated polyplex with optimized PEG shielding enhances gene introduction in lungs by minimizing inflammatory responses", Mol. Ther., 20(6), 1196-1203, 2012. DOI: 10.1038/mt.2012.20 |
| 9. | M. Kumagai, S. Shimoda, R. Wakabayashi, Y. Kunisawa, T. Ishii, K. Osada, K. Itaka, N. Nishiyama, K. Kataoka, K. Nakano, "Effective transgene expression without toxicity by intraperitoneal administration of PEG-detachable polyplex micelles in mice with peritoneal dissemination", J. Control. Release, 160(3), 542-551, 2012. DOI: 10.1016/j.jconrel.2012.03.021 |
| 10. | K. Miyazaki, Y. Morimoto, N. Nishiyama, Y. Maekawa, W.-Z. Hu, K. Nakatate, K. Kaneda, N. Shinomiya, K. Kataoka, "A novel homogeneous irradiation fiber probe for whole bladder wall photodynamic therapy", Lasers Surg. Med., 44(5), 413-420, 2012. DOI: 10.1002/lsm.22010 |
| 11. | T. Anzai, R. Kusama, H. Kodama. S. Sengoku, "Holistic observation and monitoring of the impact of interdisciplinary academic research projects: an empirical assessment in Japan", Technovation, 32(6), 345-57, 2012. DOI: 10.1016/j.technovation.2011.12.003 |
| 12. | H. Takemoto, K. Miyata, T. Ishii, S. Hattori, S. Osawa, N. Nishiyama, K. Kataoka, "Accelerated polymer-polymer click conjugation by freeze-thaw treatment", Bioconjugate Chem., 23(8), 1503-1506, 2012. DOI: 10.1021/bc300182y |
| 13. | K. Osada, H. Cabral, Y. Mochida, S.-E. Lee, K. Nagata, T. Matsuura, M. Yamamoto, Y. Anraku, A. Kishimura, N. Nishiyama, K. Kataoka, "Bioactive polymeric metallosomes self-assembled through block copolymer-metal complexation", J. Am. Chem. Soc., 134(32), 13172-13175, 2012. DOI: 10.1021/ja304615y |
| 14. | F. Pittella, K. Miyata, Y. Maeda, T. Suma, S. Watanabe, Q. Chen, R. J. Christie, K. Osada, N. Nishiyama, K. Kataoka, "Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles", J. Control. Release, 161(3), 868-874, 2012. DOI: 10.1016/j.jconrel.2012.05.005 |
| 15. | T. Suma, K. Miyata, Y. Anraku, S. Watanabe, R. J. Christie, H. Takemoto, M. Shioyama, N. Gouda, T. Ishii, N. Nishiyama, K. Kataoka, "Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica endosome-disrupting polycation and detachable PEG", ACS Nano, 6(8), 6693-6705, 2012. DOI: 10.1021/nn301164a |
| 16. | M. Sanjoh, K. Miyata, R. J. Christie, T. Ishii, Y. Maeda, F. Pittella, S. Hiki, N. Nishiyama, K. Kataoka, "Dual environment-responsive polyplex carriers for enhanced intracellular delivery of plasmid DNA", Biomacromolecules, 13(11), 3641-3649, 2012. DOI: 10.1021/bm301095a |
| 17. | T. Endo, K. Itaka, M. Shioyama, S. Uchida, K. Kataoka, "Gene transfection to spheroid culture system on micropatterned culture plate by polyplex nanomicelle: a novel platform of genetically-modified cell transplantation", Drug Deliv. Transl. Res., 2(5), 398-405, 2012. DOI: 10.1007/s13346-012-0091-1 |
| 18. | F. Yano, H. Hojo, S. Ohba, A. Fukai, Y. Hosaka, T. Ikeda, T. Saito, M. Hirata, H. Chikuda, H. Kawaguchi, U.-I. Chung, "A novel disease-modifying osteoarthritis drug candidate targeting Runx1", Ann. Rheum. Dis., 72(5), 748-753, 2012. DOI: 10.1136/annrheumdis-2012-201745 |
| 19. | Y. Takei, R. Iizuka, T. Ueno, T. Funatsu, "Single-molecule observation of protein folding in symmetric GroEL−(GroES)2 complexes", J. Biol. Chem., 287(49), 41118-41125, 2012. DOI: 10.1074/jbc.M112.398628 |
| 20. | M. Naito, T. Ishii, A. Matsumoto, K. Miyata, Y. Miyahara, K. Kataoka, "A phenylboronate-functionalized polyion complex micelle for ATP-triggered release of siRNA", Angew. Chem. Int. Ed., 51(43), 10751-10755, 2012. DOI: 10.1002/anie.201203360 |
| 21. | H. Hiruma, Y. Morimoto, K. Miyazaki, A. Inoue, T. Nomoto, S. Fukushima, N. Shinomiya, N. Nishiyama, K. Kataoka, "Photodynamic Therapy (PDT) and Diagnosis (PDD) with a Dendrimer Photosensitizer-encapsulated Polymeric Micelle", The Journal of Japan Society for Laser Surgery and Medicine, 33(2), 104-109, 2012 |
| 22. | H. Takehara, C. Y. Jiang, K. Uto, M. Ebara, T. Aoyagi, T. Ichiki, "Novel microfluidic valve technology based on shape memory effect of poly(ε-caprolactone)", Appl. Phys. Express, 6, 37201, 2012. DOI: 10.7567/APEX.6.037201 |
| 23. | P. Mi, H. Cabral, D. Kokuryo, M. Rafi, Y. Terada, I. Aoki, T. Saga, T. Ishii, N. Nishiyama, K. Kataoka, "Gd-DTPA-loaded polymer–metal complex micelles with high relaxivity for MR cancer imaging", Biomaterials, 34(2), 492-500, 2013. DOI: 10.1016/j.biomaterials.2012.09.030 |
| 24. | A. Vollrath, A. Schallon, C. Pietsch, S. Schubert, T. Nomoto, Y. Matsumoto, K. Kataoka, U. S. Schubert, "A toolbox of differently sized and labeled PMMA nanoparticles for cellular uptake investigations", Soft Matter, 9(1), 99-108, 2013. DOI: 10.1039/C2SM26928G |
| 25. | N. Gouda, K. Miyata, R. J. Christie, T. Suma, A. Kishimura, S. Fukushima, T. Nomoto, X. Liu, N. Nishiyama, K. Kataoka, "Silica nanogelling of environment-responsive PEGylated polyplexes for enhanced stability and intracellular delivery of siRNA", Biomaterials, 34(2), 562-570, 2013. DOI：10.1016/j.biomaterials.2012.09.077 |
| 26. | Y. Anraku, A. Kishimura, Y. Yamasaki, K. Kataoka, "Living unimodal growth of polyion complex vesicles via 2D supramolecular polymerization", J. Am. Chem. Soc., 135(4), 1423-1429, 2013. DOI: 10.1021/ja3096587 |
| 27. | S. Wu, V. Kasim, M. R. Kano, S. Tanaka, S. Ohba, Y. Miura, K. Miyata, X. Liu, A. Matsuhashi, U.-l. Chung, K. Kataoka, N. Nishiyama, M. Miyagishi, "Transcription factor YY1 contributes to tumor growth by stabilizing hypoxia factor HIF-1α in a p53-independent manner", Cancer Res., 73(6), 1787-1799, 2013. DOI: 10.1158/0008-5472.CAN-12-0366 |
| 28. | S. Uchida, K. Itaka, H. Uchida, K. Hayakawa, T. Ogata, T. Ishii, S. Fukushima, K. Osada, K. Kataoka, "In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle", PLoS ONE, 8(2), e56220, 2013. DOI: 10.1371/journal.pone.0056220 |
| 29. | H. Hojo, S. Ohba, K. Taniguchi, M. Shirai, F. Yano, T. Saito, T. Ikeda, K. Nakajima, Y. Komiyama, N. Nakagata, K. Suzuki, Y. Mishina, M. Yamada, T. Konno, T. Takato, H. Kawaguchi, H. Kambara, U.-I. Chung, "Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium", J. Biol. Chem., 288(14), 9924-9932, 2013. DOI: 10.1074/jbc.M112.409342 |
| 30. | K. Kato, M. Koido, M. Kobayashi, T. Akagi, T. Ichiki, "Statistical fluctuation in zeta potential distribution of nanoliposomes measured by on-chip microcapillary electrophoresis", Electrophoresis, 34(8), 1212-1218, 2013. DOI: 10.1002/elps.201200549. |
| 31. | Y. Komiyama, S. Ohba, N. Shimohata, K. Nakajima, H. Hojo, F. Yano, T. Takato, D. Docheva, C. Shukunami, Y. Hiraki, U.-I. Chung, "Tenomodulin expression in the periodontal ligament enhances cellular adhesion", PLoS ONE, 8(4), e60203, 2013. DOI: 10.1371/journal.pone.0060203 |
| 32. | Y. Maeda, H. Hojo, N. Shimohata, S. Choi, K. Yamamoto, T. Takato, U.-I. Chung, S. Ohba, "Bone healing by sterilizable calcium phosphate tetrapods eluting osteogenic molecules", Biomaterials, 34(22), 5530-5537, 2013. DOI: 10.1016/j.biomaterials.2013.03.089 |
| 33. | F. Yano, H. Hojo, S. Ohba, T. Saito, M. Honnami, M. Mochizuki, T. Takato, H. Kawaguchi, U.-I. Chung, "Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration", Biomaterials, 34(22), 5581-5587, 2013. DOI: 10.1016/j.biomaterials.2013.04.008 |
| 34. | K. Kato, M. Kobayashi, N. Hanamura, T. Akagi, N. Kosaka, T. Ochiya, T. Ichiki, "Electrokinetic evaluation of individual exosomes by on-chip microcapillary electrophoresis with laser dark-field microscopy", Jpn. J. Appl. Phys., In press, 2013. |
| 35. | S. Choi, J. Lee, K. Igawa, I. L. Liu, M. Honnami, S. Suzuki, R. Nishimura, U.-I. Chung, N. Sasaki, M. Mochizuki, "Changes in bone regeneration by trehalose coating and basic fibroblast growth factor after implantation of tailor-made bone implants in dogs", J. Vet. Med. Sci., In press, 2013. DOI: 10.1292/jvms.12-0244 |
| 36. | N. Kosaka, T. Ochiya, "Unraveling the mystery of cancer by secretory microRNA: horizontal microRNA transfer between living cells", Front. Genet., 2, 97, 2012. DOI: 10.3389/fgene.2011.00097 |
| 37. | K. Hagiwara, N. Kosaka, Y. Yoshioka, R. U. Takahashi, F. Takeshita, T. Ochiya, "Stilbene derivatives promote Ago2-dependent tumour-suppressive microRNA activity", Sci. Rep., 2, 314, 2012. DOI: 10.1038/srep00314 |
| 38. | Y. Matsumura, "Cancer stromal targeting (CAST) therapy", Adv. Drug Deliv. Rev., 64(8), 710-719, 2012. DOI: 10.1016/j.addr.2011.12.010 |
| 39. | Y. Yoshioka, N. Kosaka, T. Ochiya, T. Kato, "Micromanaging iron homeostasis - Hypoxia-inducible micro-RNA-210 suppresses iron homeostasis-related proteins", J. Biol. Chem., 287(41), 34110-34119, 2012. DOI: 10.1074/jbc.M112.356717 |
| 40. | N. Kosaka, H. Iguchi, Y. Yoshioka, K. Hagiwara, F. Takeshita, T. Ochiya, "Competitive interactions of cancer cells and normal cells via secretory microRNAs", J. Biol. Chem., 287(2), 1397-1405, 2012. DOI: 10.1074/jbc.M111.288662 |
| 41. | S. Murata, Y. Koga, Y. Moriya, T. Akasu, S. Fujita, S. Yamamoto, Y. Kakugawa, Y. Ohtake, N. Saito, Y. Matsumura, "Application of miRNA expression analysis on exfoliated colonocytes for colorectal cancer diagnosis", Gastroint. Cancer Target. Ther., 2, 11-18, 2013. DOI: http://dx.doi.org/10.2147/GICTT.S30927 |
| 42. | M. Yasunaga, S. Manabe, D. Tarin, Y. Matsumura, "Tailored immunoconjugate therapy depending on a quantity of tumor stroma", Cancer Sci., 104(2), 231-237, 2013. DOI: 10.1111/cas.12062 |
| 43. | A. Takahashi, Y. Yamamoto, M. Yasunaga, Y. Koga, J. Kuroda, M. Takigahira, M. Harada, H. Saito, T. Hayashi, Y. Kato, T. Kinoshita, N. Ohkohchi, I. Hyodo, Y. Matsumura, "NC-6300, an epirubicin-incorporating micelle, extends the antitumor effect and reduces the cardiotoxicity of epirubicin", Cancer Sci., In press, 2013. DOI: 10.1111/cas.12153 |
| 44. | N. Yamazaki, Y. Koga, S. Yamamoto, Y. Kakugawa, Y. Otake, R. Hayashi, N. Saito, Y. Matsumura, "Application of the fecal microRNA test to the residuum from the fecal occult blood test", Jpn. J. Clin. Oncol., In press, 2013. DOI: 10.2147/GICTT.S30927 |
| 45. | T. Goda, Y. Maeda, Y. Miyahara, "Simultaneous monitoring of protein adsorption kinetics using a quartz crystal microbalance and field-effect transistor integrated device", Anal. Chem., 84(17), 7308-7314, 2012. DOI: 10.1021/ac3015092 |
| 46. | T. Goda, K. Masuno, J. Nishida, N. Kosaka, T. Ochiya, A. Matsumoto, Y. Miyahara, "A label-free electrical detection of exosomal microRNAs using microelectrode array", Chem. Commun., 48(98), 11942-11944, 2012. DOI: 10.1039/C2CC36111F |
| 47. | T. Goda, Y. Miyahara, "Label-free and reagent-less protein biosensing using aptamer-modified extended-gate field-effect transistors", Biosens. Bioelectron., 45, 89-94, 2013. DOI: 10.1016/j.bios.2013.01.053 |
| 48. | A. Matsumoto, H. Matsumoto, Y. Maeda, Y. Miyahara, "Simple and robust strategy for potentiometric detection of glucose using fluorinated phenylboronic acid self-assembled monolayer", Biochim. Biophys. Acta, In press, 2013. DOI: 10.1016/j.bbagen.2013.03.004 |
| 49. | J. Kershaw, C. Leuze, I. Aoki, T. Obata, I. Kanno, H. Ito, Y. Yamaguchi, H. Handa, "Systematic changes to the apparent diffusion tensor of in vivo rat brain measured with an oscillating-gradient spin-echo sequence", NeuroImage, 70, 10-20, 2013. DOI: 10.1016/j.neuroimage.2012.12.036 |
| 50. | T. Toyota, N. Ohguri, K. Naruyama, M. Fujinami, T. Saga, "Giant vesicles containing superparamagnetic iron oxide as biodegradable cell-tracking MRI probes", Anal. Chem., 84(9), 3952-3957, 2013. DOI: 10.1021/ac2031354 |
| 51. | E. Tanimoto, S. Karasawa, S. Ueki, N. Nitta, I. Aoki, N. Koga, "Unexpectedly large water-proton relaxivity of TEMPO incorporated into micelle-oligonucleotides", RSC Adv., 3, 3531-3534, 2013. DOI: 10.1039/C3RA22372H |
| 52. | D. Kokuryo, Y. Anraku, A. Kishimura, S. Tanaka, M. R. Kano, J. Kershaw, T. Saga, I. Aoki, K. Kataoka, "SPIO-PICsome: development of a highly sensitive and stealth-capable MRI nano-agent for tumor detection using SPIO-loaded unilamellar polyion complex vesicles (PICsomes)", J. Control. Release, In press, 2013. DOI: 10.1016/j.jconrel.2013.03.016 |
| 53. | H. Arata, H. Komatsu, A. Han, K. Hosokawa, M. Maeda, "Rapid microRNA detection using power-free microfluidic chip: coaxial stacking effect enhances the sandwich hybridization", Analyst, 137, 3234-3237, 2012. DOI: 10.1039/c2an16154k |
| 54. | H. Arata, H. Komatsu, K. Hosokawa, M. Maeda, "Rapid and sensitive microRNA detection with laminar flow-assisted dendritic amplification on power-free microfluidic chip", PLoS ONE, 7(11), e48329, 2012. DOI: 10.1371/journal.pone.0048329 |
| 55. | A. Han, K. Hosokawa, M. Maeda, "Application of microchip phosphate-affinity electrophoresis to measurement of protease activity in complex samples", Anal. Biochem., 432(1), 8-10, 2013. DOI: 10.1016/j.ab.2012.09.016 |
| 56. | K. Takada, J. Okada, K. Nakamura, S. Yoshizawa, S. Umemura, "High voltage staircase drive circuit for triggered high-intensity focused ultrasound treatment", Jpn. J. Appl. Phys., 51(7), 07GF23, 2012. DOI: 10.1143/JJAP.51.07GF23 |
| 57. | A. Wada, N. Abe, H. Nakamoto, T. Suzuki, Y. Muragaki, "Novel high-intensity focused ultrasound therapy using triggered pulse to reduce therapeutic time", J Tokyo Wom Med Univ., 82(4), 216-221, 2012． |