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Development of a safe liver sinusoidal wall coating agent to significantly increase the efficacy of gene therapy drugs

For the first time in the world, Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine (Director General: Kazunori Kataoka, Location: Kawasaki-ku Kawasaki City, Abbreviation: iCONM) has succeeded in controlling the clearance of gene therapy drugs at the liver sinusoidal wall by developing a reagent for the Selective and transient coating of the liver sinusoidal walls. This was collaborative research with Dr. Kensuke Osada from the National Institute for Quantum Science and Technology, (Director: Toshio Hirano, Location: Chiba City Chiba Pref., Abbreviation: QST)and Dr. Satoshi Uchida from Department of Bioengineering, Graduate School of Engineering, The University of Tokyo.

The result of this research was published in Science Advances (Impact Factor=12.804) issued by AAAS.

At the press conference held online on Friday, June 26, Kazunori Kataoka, Director General, Innovation Center of NanoMedicine; Satoshi Uchida, Assistant Professor, Department of Bioengineering, Graduate School of Engineering, The University of Tokyo; Dirisala Anjaneyulu, Research Scientist, Innovation Center of NanoMedicine; Kensuke Osada, Senior Researcher, National Institutes for Quantum and Radiological Science and Technology; participated in the session, and there were deep and insightful discussions with journalists from the science department of general newspapers, and bio journals.

Click here for the paper

Click here for press release

【Kazunori Kataoka iCONM Director General】

【Satoshi Uchida Assistant Professor, The University of Tokyo】

【Dirisala Anjaneyulu iCONM Research Scientist】

【Kensuke Osada, Senior Researcher, QST】

【Web conference room】

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