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論文

西山ラボ（2015～現在）

論文

  1. Y. Honda, T. Nomoto, M. Matsui, H. Takemoto, Y. Miura, N. Nishiyama, Sequentially self-assembled nanoreactor comprising tannic acid and phenylboronic acid-conjugated polymers inducing tumor-selective enzymatic activity. ACS Appl. Mater. Inter. 13(46) 54850-54859 (2021) (10.1021/acsami.1c20188)
  2. H. Guo, T. Nomoto, S. E. Muttaqien, X. Sun, K. Komoto, M. Matsui, Y. Miura, N. Nishiyama, Polymeric iron chelators enhancing pro-oxidant antitumor efficacy of vitamin C by inhibiting the extracellular fenton reaction. Mol Pharm. 18(12) 4475-4485(2021) (doi: 10.1021/acs.molpharmaceut.1c00673)
  3. Y. Honda, T. Nomoto, H. Takemoto, M. Matsui, K. Taniwaki, H. Guo, Y. Miura, N. Nishiyama, Systemically applicable glutamine-functionalized polymer exerting multivalent interaction with tumors overexpressing ASCT2. ACS Applied Bio Materials, 4(10) 7402-7407(2021) (10.1021/acsabm.1c00771)
  4. T. Nomoto, Y. Yao, Y. Inoue, M. Suzuki, K. Kanamori, H. Takemoto, M. Matsui, K. Tomoda, N. Nishiyama, Fructose-functionalized polymers to enhance therapeutic potential of p-boronophenylalanine for neutron capture therapy. J. Control. Release 332 184-193 (2021)(10.1016/j.jconrel.2021.02.021)
  5. S. Muttaqien, T. Nomoto, X. Dou, H. Takemoto, M. Matsui, N. Nishiyama, Photodynamic therapy using LCST polymers exerting pH-responsive isothermal phase transition. J. Control. Release 328 608-616 (2020) (10.1016/j.jconrel.2020.09.036)
  6. X. Sun, T. Nomoto, H. Takemoto, M. Matsui, H. Guo, Y. Sun, Y. Miura, N. Nishiyama, Potential urinary monitoring of the enhanced permeability and retention effect using MMP-2-responsive poly(ethylene glycol) derivatives. J. Control. Release 329 513-523 (2020) (doi: 10.1016/j.jconrel.2020.09.004)
  7. K. Komoto, T. Nomoto, S. Muttaqien, H. Takemoto, M. Matsui, Y. Miura, N. Nishiyama, Iron chelation cancer therapy using hydrophilic block copolymers conjugated with deferoxamine. Cancer Sci. 112 410-421(2021) (doi: 10.1111/cas.14607)
  8. Y. Honda, T. Nomoto, M. Matsui, H. Takemoto, Y. Kaihara, Y. Miura, N. Nishiyama, Sequential self-assembly using tannic acid and phenylboronic acid-modified copolymers for potential protein delivery. Biomacromolecules 21(9) 3826–3835 (2020) (doi: 10.1021/acs.biomac.0c00903)
  9. T. Nomoto, Y. Inoue, Y. Yao, M. Suzuki, K. Kanamori, H. Takemoto, M. Matsui, K. Tomoda, N. Nishiyama, Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism. Sci. Adv. 6 (4) eaaz1722 (2020) (doi: 10.1126/sciadv.aaz1722)
  10. H. Takemoto, T. Inaba, T. Nomoto, M. Matsui, X. Liu, M. Toyoda, Y. Honda, K. Taniwaki, N. Yamada, J. Kim, K. Tomoda, N. Nishiyama, Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects. Biomaterials 235 119804 (2020) (doi: 10.1016/j.biomaterials.2020.119804)
  11. H. Takemoto, C.L. Wang CL, T. Nomoto, M. Matsui, K. Tomoda, N. Nishiyama, Pyruvate responsiveness based on α-oxohydrazone formation for intracellular siRNA release from polyion complex-based carriers. Biomacromolecules 20 (6) 2305-2314 (2019) (doi: 10.1021/acs.biomac.9b00261)
  12. S.E. Muttaqien, T. Nomoto, H. Takemoto, M. Matsui, K. Tomoda, N. Nishiyama, Poly(N-isopropylacrylamide)-based polymer inducing isothermal hydrophilic-to-hydrophobic phase transition via detachment of hydrophilic acid-labile moiety. Biomacromolecules 20 (4) 1493-1504 (2019) (doi: 10.1021/acs.biomac.8b01465)
  13. S.E. Muttaqien, T. Nomoto, H. Takemoto, M. Matsui, K. Tomoda, N. Nishiyama, Poly(N-isopropylacrylamide)-based polymer inducing isothermal hydrophilic-to-hydrophobic phase transition via detachment of hydrophilic acid-labile moiety. Biomacromolecules in press (2018) (DOI: 10.1021/acs.biomac.8b01465)
  14. T. Chida, Y. Miura, H. Cabral, T. Nomoto, K. Kataoka, N. Nishiyama, Epirubicin-loaded polymeric micelles effectively treat axillary lymph nodes metastasis of breast cancer through selective accumulation and pH-triggered drug release. J. Control. Release 292 130-140 (2018) (DOI: 10.1016/j.jconrel.2018.10.035)
  15. R. Toshiyama R, M. Konno, H. Eguchi, H. Takemoto, T. Noda, A. Asai, J. Koseki, N. Haraguchi, Y. Ueda, K. Matsushita, K. Asukai, T. Ohashi, Y. Iwagami, D. Yamada, D. Sakai, T. Asaoka, T. Kudo, K. Kawamoto, K. Gotoh, S. Kobayashi, T. Satoh, Y. Doki, N. Nishiyama, M. Mori, H. Ishii, Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells. Oncogene 38 (2) 244-260 (2019) (DOI: 10.1038/s41388-018-0406-x.)
  16. X. Dou, T. Nomoto, H. Takemoto, M. Matsui, K. Tomoda, N. Nishiyama, Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers. Sci. Rep. 8 (1) 6077 (2018) (DOI:10.1038/s41598-018-26593-0)
  17. A.-H. Ranneh, H. Takemoto, S. Sakuma, A. Awaad, T. Nomoto, Y. Mochida, M. Matsui, K. Tomoda, M. Naito, N. Nishiyama, An ethylenediamine-based switch to control the polyzwitterion charge at tumorous pH for effective tumor accumulation of coated nanomaterials. Angew. Chem. Int. Ed. 57(18) 5057-5061 (2018) (DOI: 10.1002/anie.201801641)
  18. Y. Anraku, H. Kuwahara, Y. Fukusato, A. Mizoguchi, T. Ishii, K. Nitta, Y. Matsumoto, K. Toh, K. Miyata, S. Uchida, K. Nishina, K. Osada, K. Itaka, N. Nishiyama, H. Mizusawa, T. Yamasoba, T. Yokota*, K. Kataoka, Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain. Nature Commun. 8 1001 (2017) (DOI: 10.1038/s41467-017-00952-3)
  19. M. Maeda, Y. Muragaki, J. Okamoto, S. Yoshizawa, N. Abe, H. Nakamoto, H. Ishii, K. Kawabata, S. Umemura, N. Nishiyama, K. Kataoka, H. Iseki, Sonodynamic therapy based on combined use of low dose administration of epirubicin-incorporating drug delivery system and focused ultrasound. Ultrasound Med. Biol. 43 (10) 2295-2301 (2017) (DOI: 10.1016/j.ultrasmedbio.2017.06.003)
  20. K. Miyano, H. Cabral, Y. Miura, Y. Matsumoto, Y. Mochida, H. Kinoh, K. Iwata, O. Nagato, H. Saya, N. Nishiyama, K. Kataoka, T. Yamasoba, cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells. J. Control. Release 261 275-286 (2017) (DOI: 10.1016/j.jconrel.2017.06.021)
  21. S. Quader, X. Liu, Y. Chen, P. Mi, T. Chida, T. Ishii, Y. Miura, N. Nishiyama, H. Cabral, K. Kataoka, cRGD peptide-installed epirubicin-loaded polymeric micelles for effective targeted therapy against brain tumors. J. Control. Release 258 56-66 (2017) (DOI: 10.1016/j.jconrel.2017.04.033)
  22. N. Yamada, Y. Honda, H. Takemoto, T. Nomoto, M. Matsui, K. Tomoda, M. Konno, H. Ishii, M. Mori, N. Nishiyama, Engineering tumour cell-binding synthetic polymers with sensing dense transporters associated with aberrant glutamine metabolism. Sci. Rep. 7 (1) 6077 (2017) (DOI: 10.1038/s41598-017-06438-y.)
  23. H. Taniguchi, D. Hoshino, C. Moriya, H. Zembutsu, N. Nishiyama, H. Yamamoto, K. Kataoka, K. Imai, Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer. Oncotarget, Oncotarget 8 29 46856-46874 (2017) (DOI: 10.18632/oncotarget.16776)
  24. P. Mi*, H. Yanagie, N. Dewi, H.-C. Yen, X. Liu, M. Suzuki, Y. Sakurai, K. Ono, H. Takahashi, H. Cabral*, K. Kataoka*, N. Nishiyama*, Block copolymer-boron cluster conjugate for effective boron neutron capture therapy of solid tumors. J. Control. Release, 254 1-9 (2017) (DOI: 10.1016/j.jconrel.2017.03.036)
  25. M. Naito, R, Azuma, H. Takemoto, M. Hori, N. Yoshinaga, S. Osawa, R. Kamegawa, H.J. Kim, T. Ishii, N. Nishiyama, K. Miyata*, K. Kataoka*, Multilayered polyion complexes with dissolvable silica layer covered by controlling densities of cRGD-conjugated PEG chains for cancer-targeted siRNA delivery. J. Biomater. Sci. Polym. Ed., in press. (DOI: 10.1080/09205063.2017.1301775)
  26. C. H. Huang, H. Takemoto*, T. Nomoto, K. Tomoda, M. Matsui, N. Nishiyama*, Utility of the 2-nitrobenzenesulfonamide group as a chemical linker for enhanced extracellular stability and cytosolic cleavage in siRNA-conjugated polymer systems. ChemMedChem 12 (1) 19-22 (2017) (DOI: 10.1002/cmdc.201600488)
  27. N. F. Che Harun, H. Takemoto*, T. Nomoto, K. Tomoda, M. Matsui, N. Nishiyama*, Artificial control of gene silencing activity based on siRNA conjugation with polymeric molecule having coil–globule transition behavior. Bioconjugate Chem. 27 (9) 1961-1964 (2016) (DOI: 10.1021/acs.bioconjchem.6b00322)
  28. H. Hino, M. Kamiya, K. Kitano, K. Mizuno, S. Tanaka, N. Nishiyama, K. Kataoka, Y. Urano*, J. Nakajima*, Rapid cancer fluorescence imaging using a γ-glutamyltranspeptidase-specific probe for primary lung cancer. Transl Oncol. 9 (3) 203-210 (2017) (DOI: 10.1016/j.tranon.2016.03.007)
  29. M. Iijima, D. Ulkoski, S. Sakuma, D. Matsukuma, N. Nishiyama, H. Otsuka, C. Scholz*, Synthesis of PEGylated poly(amino acid) pentablock copolymers and their self-assembly. Polymer International 65 (10) 1132-1141 (2016) (DOI: 10.1002/pi.5159)
  30. P. Mi, D. Kokuryo, H. Cabral, H. Wu, Y. Terada, T. Saga, I. Aoki*, N. Nishiyama*, K. Kataoka*, A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy. Nature Nanotech. 11 (8) 724-730 (2016) (DOI: 10.1038/nnano.2016.72)
  31. H. Kinoh, Y. Miura, T. Chida, X. Liu, K. Mizuno, S. Fukushima, Y. Morodomi, N. Nishiyama, H. Cabral*, K. Kataoka*, Nanomedicines eradicating cancer stem-like cells in vivo by pH-triggered intracellular cooperative action of loaded drugs. ACS Nano 10 (6) 5643-5655 (2016) (DOI: 10.1021/acsnano.6b00900)
  32. Y. Matsumoto, Y. Miyamoto, H. Cabral, Y. Matsumoto, K. Nagasaka, S. Nakagawa*, D. Maeda, T. Yano, K. Oda, K. Kawana, N. Nishiyama, K. Kataoka*, T. Fujii, Enhanced efficacy against cervical carcinomas through polymeric micelles physically incorporating the proteasome inhibitor MG132. Cancer Sci. 107 (6) 773-781 (2016) (DOI: 10.1111/cas.12926)
  33. Y. Matsumoto, J. W. Nichols, K. Toh, T. Nomoto, H. Cabral, Y. Miura, R. J. Christie, N. Yamada, T. Ogura, M. R. Kano, Y. Matsumura, N. Nishiyama, T. Yamasoba, Y. -H. Bae*, K. Kataoka*, Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery. Nature Nanotech. 11 (6) 533-538 (2016) (DOI: 10.1038/nnano.2015.342) [Highlighted in Nature Nanotech. 11 (6) 494-496 (2016)]
  34. H. Nishida, Y. Matsumoto, K. Kawana*, R. J. Christie, M. Naito, B. -S. Kim, K. Toh, H. -S. Min, Y. Yi, Y. Matsumoto, H. -J. Kim, K. Miyata*, A. Taguchi, K. Tomio, A. Yamashita, T. Inoue, H. Nakamura, A. Fujimoto, M. Sato, M. Yoshida, K. Adachi, T. Arimoto, O. Wada-Hiraike, K. Oda, T. Nagamatsu, N. Nishiyama, K. Kataoka*, Y. Osuga, T. Fujii, Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes. J. Control. Release 231 29-37 (2016) (DOI: 10.1016/j.jconrel.2016.03.016)
  35. M. Wang, Y. Miura, K. Tsuchihashi, K. Miyano, O. Nagano, M. Yoshikawa, A. Tanabe, J. Makino, Y. Mochida, N. Nishiyama, H. Saya, H. Cabral*, K. Kataoka*, Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines. J. Control. Release 230 26-33 (2016) (DOI: 10.1016/j.jconrel.2016.03.038)
  36. T. Nomoto, S. Fukushima, M. Kumagai, K. Miyazaki, A. Inoue, P. Mi, Y. Maeda, K. Toh, Y. Matsumoto, Y. Morimoto, A. Kishimura, N. Nishiyama*, K. Kataoka*, Calcium phosphate-based organic-inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy. Biomater. Sci. 4 (5) 826-838 (2016) (DOI: 10.1039/C6BM00011H)
  37. K. Hayashi, H. Chaya, S. Fukushima, S. Watanabe, H. Takemoto, K. Osada, N. Nishiyama, K. Miyata*, K. Kataoka*, Influence of RNA strand rigidity on polyion complex formation with block catiomers. Macromol. Rapid Commun. 37 (6) 486-493 (2016) (DOI: 10.1002/marc.201500661)
  38. N. Dewi, P. Mi, H. Yanagie*, Y. Sakurai, Y. Morishita, M. Yanagawa, T. Nakagawa, A. Shinohara, T. Matsukawa, K. Yokoyama, H. Cabral, M. Suzuki, Y. Sakurai, H. Tanaka, K. Ono, N. Nishiyama, K. Kataoka, H. Takahashi, In vivo evaluation of neutron capture therapy effectivity using calcium phosphate-based nanoparticles as Gd-DTPA delivery agent. J. Cancer Res. Clin. Oncol. 142 (4) 767-775 (2016) (DOI: 10.1007/s00432-015-2085-0)
  39. H. Uchida, K. Itaka, S. Uchida, T. Ishii, T. Suma, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka*, Synthetic polyamines to regulate mRNA translation through the preservative binding of eukaryotic initiation factor 4E to the cap structure. J. Am. Chem. Soc. 138 (5) 1478-1481 (2016) (DOI: 10.1021/jacs.5b11726)
  40. A. Kim, Y. Miura, T. Ishii, O. F. Mutaf, N. Nishiyama, H. Cabral, K. Kataoka*, Intracellular delivery of charge-converted monoclonal antibodies by combinatorial design of block/homo polyion complex micelles. Biomacromolecules 17 (2) 446-453 (2016) (DOI: 10.1021/acs.biomac.5b01335)
  41. Y. Anraku, A. Kishimura*, M. Kamiya, S. Tanaka, T. Nomoto, K. Toh, Y. Matsumoto, S. Fukushima, D. Sueyoshi, M. R. Kano, Y. Urano, N. Nishiyama, K. Kataoka*, Systemically injectable enzyme-loaded polyion complex vesicles as in vivo nanoreactors functioning in tumors. Angew. Chem. Int. Ed. 128 (2) 570-575 (2016) (DOI: 10.1002/ange.201508339)
  42. M. Tangsangasaksri, H. Takemoto, M. Naito, Y. Maeda, D. Sueyoshi, H. -J. Kim, Y. Miura, J. -Y. Ahn, R. Azuma, N. Nishiyama, K. Miyata*, K. Kataoka*, siRNA-loaded polyion complex micelle decorated with charge-conversional polymer tuned to undergo stepwise response to intra-tumoral and intra-endosomal pHs for exerting enhanced RNAi efficacy. Biomacromolecules 17 (1) 246-255 (2016) (DOI: 10.1021/acs.biomac.5b01334)
  43. J. Makino, H. Cabral*, Y. Miura, Y. Matsumoto, M. Wang, H. Kinoh, Y. Mochida, N. Nishiyama, K. Kataoka*, CRGD-installed polymeric micelles loading platinum anticancer drugs enable cooperative treatment against lymph node metastasis. J. Control. Release 220 PartB 783-791 (2015) (DOI:10.1016/j.jconrel.2015.10.017)
  44. M. Murakami*, K. Nishina, C. Watanabe, K. Y. Tanaka, W. Piao, H. Kuwahara, Y. Horikiri, K. Miyata, N. Nishiyama, K. Kataoka, M. Yoshida, H. Mizusawa, T. Yokota*, Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route. Sci. Rep. 5 17035 (2015) (DOI: 10.1038/srep17035)
  45. Y. Miura, A. B. Tsuji, A. Sugyo, H. Sudo, I. Aoki, M. Inubushi, M. Yashiro, K. Hirakawa, H. Cabral, N. Nishiyama, T. Saga*, K. Kataoka*, Polymeric micelle platform for multimodal tomographic imaging to detect scirrhous gastric cancer. ACS Biomater. Sci. Eng. 1 (11) 1067-1076 (2015) (DOI: 10.1021/acsbiomaterials.5b00142)
  46. K. S. –Kato*, K. Nanjo, H. Kusuhara, N. Nishiyama, K. Kataoka, T. Kawanishi, H. Okuda, Y. Goda, Effect of knockout of Mdr1a and Mdr1b ABCB1 genes on the systemic exposure of a doxorubicin-conjugated block copolymer in mice. Mol. Pharm. 12 19 3175-3183 (2015) (DOI: 10.1021/acs.molpharmaceut.5b00234)
  47. P. Mi, N. Dewi, H. Yanagie, D. Kokuryo, M. Suzuki, Y. Sakurai, Y. Li, I. Aoki, K. Ono, H. Takahashi, H. Cabral, N. Nishiyama*, K. Kataoka*, Hybrid calcium phosphate-polymeric micelles incorporating gadolinium chelates for imaging-guided gadolinium neutron capture tumor therapy. ACS Nano 9 (6) 5913-5921 (2015) (DOI: 10.1021/acsnano.5b00532)
  48. W. Kawamura, Y. Miura, D. Kokuryo, K. Toh, N. Yamada, T. Nomoto, Y. Matsumoto, D. Sueyoshi, X. Liu, I. Aoki, M. R. Kano, N. Nishiyama, T. Saga, A. Kishimura, K. Kataoka*, Density-tunable conjugation of cyclic RGD ligands with polyion complex vesicles for the neovascular imaging of orthotopic glioblastomas. Sci. Technol. Adv. Mater. 16 (3) 035004 (2015) (DOI: 10.1088/1468-6996/16/3/035004)
  49. H. Cabral, J. Makino, Y. Matsumoto, P. Mi, H. Wu, T. Nomoto, K. Toh, N. Yamada, Y. Higuchi, S. Konishi, M. R. Kano, H. Nishihara, Y. Miura, N. Nishiyama, K. Kataoka*, Systemic targeting of lymph node metastasis through the blood vascular system by using size-controlled nanocarriers. ACS Nano 9 (5) 4957-4967 (2015) (DOI: 10.1021/nn5070259)
  50. H. Ogawa, X. Wu, K. Kawamoto, N. Nishida, M. Konno, J. Koseki, H. Matsui, K. Noguchi, N. Gotoh, T. Yamamoto, K. Miyata, N. Nishiyama, H. Nagano, H. Yamamoto, S. Obika, K. Kataoka, Y. Doki, M. Mori*, H. Ishii*, MicroRNAs induce epigenetic reprogramming and suppress malignant phenotypes of human colon cancer cells. PLOS ONE 10(5) e0127119 (2015) (DOI: 10.1371/journal.pone.0127119)
  51. J. -Y. Ahn, Y. Miura, N. Yamada, T. Chida, X. Liu, A. Kim, R. Sato, R. Tsumura, Y. Koga, M. Yasunaga, N. Nishiyama, Y. Matsumura, H. Cabral, K. Kataoka*, Antibody fragment-conjugated polymeric micelles incorporating platinum drugs for targeted therapy of pancreatic cancer. Biomaterials 39 23-30 (2015) (DOI: 10.1016/j.biomaterials.2014.10.069)

総説（英文）

  1. T. Nomoto, N. Nishiyama, Design of drug delivery systems for physical energy-induced chemical surgery. Biomaterials 178 583-596 (2018) (DOI: 10.1016/j.biomaterials.2018.03.038)
  2. H. Takemoto, N. Nishiyama, Functional polymer-based siRNA delivery carrier that recognizes site- specific biosignals. J. Control. Release 267 90-99 (2017) (DOI: 10.1016/j.jconrel.2017.09.005)
  3. P. Mi, F. Wang, N. Nishiyama, H. Cabral*, Molecular cancer imaging with polymeric nanoassemblies: from tumor detection to theranostics. Macromol. Biosci. 17 (1) (2017) (DOI: 10.1002/mabi.201600305)
  4. N. Nishiyama*, Y. Matsumura, K. Kataoka, Development of polymeric micelles for targeting intractable cancers. Cancer Sci. 107 (7) 867-874 (2016) (DOI: 10.1111/cas.12960)
  5. K. S. Kato*, N. Nishiyama, M. Kozaki, T. Nakanishi, Y. Matsuda, M. Hirano, H. Hanada, S. Hisada, H. Onodera, H. Harashima, Y. Matsumura, K. Kataoka, Y. Goda, H. Okuda, T. Kawanishi, General considerations regarding the in vitro and in vivo properties of block copolymer micelle products and their evaluation. J. Control. Release 210 76-83 (2015) (DOI: 10.1016/j.jconrel.2015.05.259)

総説（和文）

  1. 西山伸宏 『核酸医薬とがん』　特集 核酸医薬の現状と展望　最新医学　最新医学社（大阪) 73(6) 64-69 (2018)
  2. 西山伸宏 『OPINION イメージングが切り開くDDS研究の新時代』　Drug Delivery System 33(3): 170 (2018)
  3. 西山伸宏 『2-4スマート機能を具備した高分子ミセル型DDS 第II章 バイオマテリアルの種類と医療応用』　ヴィジュアルでわかるバイオマテリアル（編 古薗勉 岡田正弘）学研メディカル秀潤社（東京) p.113 (2018)
  4. 西山伸宏 『ペプチドリガンドを搭載したドラッグデリバリーシステム(DDS)の創製』
    生化学 日本生化学会（東京) 89 (1) 39-43 (2017)
  5. 西山伸宏 『薬物を高機能ナノマシンに搭載して確実に送り届ける』
    日経サイエンス 日経サイエンス社（東京）2月号 p.104 (2017)
  6. 西山伸宏 『微小環境を可視化するナノDDS造影剤 -DDSのコンパニオン診断の実現を目指して-』
    ファルマシア 日本薬学会(東京) 52 (11) 1025-1029 (2016)
  7. 西山伸宏 片岡一則 『ドラッグデリバリーシステムを用いた膵がん治療 胆と膵』
    医学図書出版(東京) 36(10) 1189-1193化学同人(京都) 88-96 (2015)
  8. 西山伸宏 片岡一則 『10章 ターゲティング型DDS がんの分子イメージング（編集 浦野泰照）』
    化学同人(京都) 88-96 (2015)
  9. 西山伸宏 片岡一則 『ドラッグデリバリーシステムを用いた膵癌治療 胆と膵』
    医学図書出版(東京) 36(10) 1189-1193 (2015)
  10. 西山伸宏 片岡一則 ＜編集＞『特集 ナノDDS革命 革新的ドラッグデリバリーシステムが難治疾患治療に光をもたらす』
    Overview 細胞工学 秀潤社(東京)　34(10)　926-928 (2015)
  11. 西山伸宏 片岡一則 『高分子ミセル型ナノマシンが拓く未来医療』
    細胞工学 秀潤社(東京) 34(10) 929-934 (2015)
  12. 西山伸宏 ＜編集＞『特集 アカデミアと企業の連携による新たなナノテクの創成』
    Drug Delivery System 日本DDS学会（川崎） 30(3) 179 (2015)
  13. 西山伸宏 『ナノメディシン-副作用のない理想的な医薬品の実現に向けて』
    現代化学 東京化学同人 (東京) 528(2015年3月号) 42-45 (2015)
  14. 西山伸宏 『提言 課題をどのように設定するか-社会は研究の窓口- バイオマテリアル-生体材料-』
    日本バイオマテリアル学会(東京) 33(2) 120 (2015)

著書

  1. 片岡一則　原島秀吉　編 『ドラッグキャリア設計入門 DDSからナノマシンまで』
    丸善出版(東京) (2019) , 1.5節、1.6節、2.1節　執筆