Research Activities

Papers

FY2024

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No.	Date	Journal	Title	Author	Remarks
35	11/19/2024	神経治療学	mRNA医薬品のワクチンを超えた中枢神経系疾患治療への展開 https://doi.org/10.15082/jsnt.41.4_676	Uchida	41 (4), 676-681 (2024)
34	11/13/2024	Mol. Sys. Des. Eng.	Dual-Labelled Polymeric Micelles for Singlet Oxygen Reporting in Biological Systems https://doi.org/10.1039/D4ME00105B	Anraku Cabral	in press
33	11/10/2024	J. Controlled Release	Poly(vinyl alcohol) potentiating an inert D-amino acid-based drug for boron neutron capture therapy http://doi.org/10.1016/j.jconrel.2024.11.017	Nishiyama	in press
32	11/4/2024	Nature Portfolio	Cap analogs with a hydrophobic photocleavable tag enable facile purification of fully capped mRNA with various cap structures https://doi.org/10.21203/rs.3.rs-2119525/v1	Uchida	in press
31	10/31/2024	Biomacromolecules	Synthesis and Optimization of Ethylenediamine-Based Zwitterion on Polymer Side Chain for Recognizing Narrow Tumorous pH Windows https://doi.org/10.1021/acs.biomac.4c01086	Miura Nishiyama	in press
30	10/31/2024	Int. J. Innovation Science	Narratives of growth of formative technological innovation systems based on a knowledge perspective: the case of medical devices https://doi.org/10.1108/IJIS-12-2023-0281	Sengoku	in press
29	10/28/2024	Therapeutic Innovation and Regulatory Science	Open Innovation and Regulatory Challenges in New Modality Development: The Pivotal Role of Contract Development and Manufacturing Organisations in Advancing Antibody Drugs https://doi.org/10.1007/s43441-024-00701-x	Sengoku	in press
28	10/18/2024	Foods	Driving Innovation Through Regulatory Design and Corporate Behaviour: A Case Study of Functional Food Industry in Japan https://doi.org/10.3390/foods13203302	Sengoku	13 (20), 3302 (2024)
27	10/16/2024	Int. J. Biological Macromolecules	Fine-tuning the cytotoxicity profile of N,N,N-trimethyl chitosan through trimethylation, molecular weight, and polyelectrolyte complex nanoparticles https://doi.org/10.1016/j.ijbiomac.2024.135805	Quader	281 (2), 135805
26	10/3/2024	J. Am. Chem. Soc.	Nanoenabled IL-15 Superagonist via Conditionally Stabilized Protein–Protein Interactions Eradicates Solid Tumors by Precise Immunomodulation https://doi.org/10.1021/jacs.4c08327	Cabral Kataoka	146 (47), 32161-32880
25	10/1/2024	Nanomedicines for Effective Cancer Therapy	Novel Core-Shell Design for Polymeric Micelles https://doi.org/10.1007/978-981-97-5288-1	Nishiyama	pp. 139-148 (2024)
24	9/26/2024	Nature Communications	Heteroduplex oligonucleotide technology boosts oligonucleotide splice switching activity of morpholino oligomers in a Duchenne muscular dystrophy mouse model https://doi.org/10.1038/s41467-024-48204-5	Miyata	15, 7530 (2024)
23	9/11/2024	Chemistry of Materials	Surface-Initiated Synergistic Disassembly of Metal-Phenolic Networks by Redox and Hydrolytic Reactions https://doi.org/10.1021/acs.chemmater.4c01724	Miyata	36 (19), 9646–9657 (2024)
22	8/28/2024	ACS Synthetic Biology	Glucosylated Nanovaccines for Dendritic Cell-Targeted Antigen Delivery and Amplified Cancer Immunotherapy https://doi.org/10.1021/acsnano.4c09053	Cabral	18 (37), 25826–25840 (2024)
21	8/14/2024	J. Drug Delivery Sci. and Tech.	A Novel Fungal-Targeted Drug Delivery System Dectin-1-Targeted-Peg-Amino Acid Polymer Block Enhances Antifungal Activity and Reduces Cytotoxicity of Amphotericin B https://doi.org/10.1016/j.jddst.2024.106073	Cabral	100, 106073 (2024)
20	8/7/2024	Nanomedicine and Nanobiotechnology	Polymer–drug and polymer–protein conjugated nanocarriers: Design, drug delivery, imaging, therapy, and clinical applications https://doi.org/10.1002/wnan.1988	Haochen	16 (4), e1988 (2024)
19	8/7/2024	Pharmaceutical Research	Quality and Safety Considerations for Therapeutic Products Based on Extracellular Vesicles https://doi.org/10.1007/s11095-024-03757-4	Ichiki	41, 1573–1594 (2024)
18	7/10/2024	Materials Horizons	Triphenylphosphonium-modified catiomers enhance in vivo mRNA delivery through stabilized polyion complexation https://doi.org/10.1039/D4MH00325J	Cabral Anraku	11, 4711-4721 (2024)
17	7/3/2024	Bioconjugate Chemistry	Size-Dependent Glioblastoma Targeting by Polymeric Nanoruler with Prolonged Blood Circulation https://doi.org/10.1021/acs.bioconjchem.4c00235	Naito Mochida Miyata	35 (8), 1154–1159 (2024)
16	7/2/2024	RSC Pharmaceutics	Tryptophan Intercalation in siRNA Drives the Formation of Polymeric Micelles with Enhanced Delivery Efficiency https://doi.org/10.1039/D4PM00142G	Cabral	1, 513-523 (2024)
15	6/25/2024	J. Photopolymer Science and Technology	Effects of Solvents on the Preparation of PLLA/PEDOT:PSS Conductive Polymer Alloy Films https://doi.org/10.2494/photopolymer.37.239	Kanda Ichiki	37 (2), 239-244 (2024)
14	6/25/2024	J. Photopolymer Science and Technology	Functionalization of Poly-L-Lactic Acid Microneedle Tips using Hydrogel Photopolymerization https://doi.org/10.2494/photopolymer.37.233	Kanda Ichiki	37 (2), 233-237 (2024)
13	6/22/2024	Microfluidics in Pharmaceutical Science (Springer)	Microfluidic Production of Inorganic Nanoparticles https://doi.org/10.1007/978-3-031-60717-2_6	Uchida	133-162 (2024)
12	6/16/2024	Small	Droplet Microfluidics Powered Hydrogel Microparticles for Stem Cell-Mediated Biomedical Applications https://doi.org/10.1002/smll.202401400	Uchida	2401400(2024)
11	6/8/2024	J. Controlled Release	Active control of pharmacokinetics using light-responsive polymer-drug conjugates for boron neutron capture therapy https://doi.org/10.1016/j.jconrel.2024.06.006	Miura Nishiyama	371 (7) 445-454 (2024)
10	6/3/2024	Chem Med Chem	Enhancing Targeted Drug Delivery through Cell-Specific Endosomal Escape https://doi.org/10.1002/cmdc.202400274	Cabral	e202400274(2024)
9	5/10/2024	Chemistry Letters	Polyion complex vesicles containing viscosity enhancer for sustained release of water-soluble low-molecular-weight drugs https://doi.org/10.1093/chemle/upae070	Anraku Fukushima	53(5),(2024)
8	5/6/2024	Social Science Research Network	A Novel Fungal-Targeted Drug Delivery System Dectin-1-Targeted-Peg-Amino Acid Polymer Block Enhances Antifungal Activity and Reduces Cytotoxicity of Amphotericin B https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4813303	Cabral	in press
7	5/1/2024	Scientific Reports	Development of a new caged intein for multi-input conditional translation of synthetic mRNA https://doi.org/10.1038/s41598-024-60809-w	Itaka	14, 9988(2024)
6	4/23/2024	Angewandte Chemie	Facile generation of heterotelechelic poly(2-oxazoline)s towards accelerated exploration of poly(2-oxazoline)-based nanomedicine https://doi.org/10.1002/anie.202404972	Van Guyse Dirisala Quader Uchida Kataoka	e202404972 (2024)
5	4/22/2024	Langmuir	Quantification of Poly(ethylene glycol) Crowding on Nanodiamonds toward Quantum Biosensor for Improved Prevention Effects on Protein Adsorption and Lung Accumulation https://doi.org/10.1021/acs.langmuir.3c03988	Osada	40(18),9471–9480(2024)
4	4/10/2024	Science and Technology for Advanced Materials	Fine tuning of the net charge alternation of polyzwitterion surfaced lipid nanoparticles to enhance cellular uptake and membrane fusion potential https://doi.org/10.1080/14686996.2024.2338785	Miura Nishiyama	25(1), 2338785(2024)
3	4/5/2024	Clinical Cancer Research	Stabilizing tumor resident mast cells restores T cell infiltration and sensitizes sarcomas to PD-L1 inhibition https://doi.org/10.1158/1078-0432.CCR-24-0246	Cabral	30(11),2582–2597(2024)
2	4/2/2024	Molecular Therapy	Carrier-free mRNA vaccine induces robust immunity against SARS-CoV-2 in mice and non-human primates without systemic reactogenicity https://doi.org/10.1016/j.ymthe.2024.03.022	Abbasi Tockery Mochida Kataoka Uchida	32(5), 1266-1283(2024)
1	4/1/2024	Cancer Science	Long noncoding RNA TUG1 promotes cisplatin resistance in ovarian cancer via upregulation of DNA polymerase eta https://doi.org/10.1111/cas.16150	Nishiyama Miyata Kataoka	115, 1910-1923 (2024)