Nov. 26. 2022 Updated
12/10/2022
Horacio CABRAL Visiting Scientist (Associate Professor, Department of Bioengineering, Graduate School of Engineering, The University of Tokyo) entitled "Polymeric micelles effectively reprogram the tumor microenvironment to potentiate nano-immunotherapy in mouse breast cancer models" has been published on Nature Communications.
▶ (12/14)Investigación y Ciencia
▶ (12/07)The University of Tokyo Press Release
▶ (12/06)EurekAlert!
▶ (12/06)PHYS-ORG News
▶ (12/06)Today's Chronic
11/26/2022
Professor Kazunori Kataoka, Director General of iCONM, has been selected to a 2022 Highly Cited Researcher in Clarivate Analytics (Web of Scinece), recognized for his exceptional research influence demonstrated by the production of multiple highly-cited papers that rank in the top 1% by citations for field and year in Web of Science.
▶List of 2022 Highly Cited Researchers
▶Researcher Page (Kazunori Kataoka)
06/25/2022
Anjaneyulu Dirisala Research Scientist entitled "Effective mRNA protection by poly(L-ornithine) synergizes with endosomal escape functionality of a charge-conversion polymer toward maximizing mRNA introduction efficiency" has been published on Macromolecular Rapid Communications (Volume 43, Issue 12, 2100754 June 2022) and selected as a back cover picture.
▶ Paper / Back Cover
04/17/2022
An article about our research "Targeted nanomedicine in cisplatin-based cancer therapeutics" was posted on EurekAlert!/AAAS.
▶ (04/09)EurekAlert！
▶ (04/12)DESCARGASKIN
▶ (04/12)Genius Interactive
▶ (04/12)AZO NANO
04/07/2022
An article about our research "Nanomedicine for brain cancer” was posted on EurekAlert!/AAAS.
▶ (04/07)EurekAlert!
▶ (04/08) News-Medical.Net (1), News-Medical.Net (2)
▶ (04/09)Trend Fool
04/06/2022
The paper entitled as “Effective mRNA Protection by Poly(l-ornithine) Synergizes with Endosomal Escape Functionality of a Charge-Conversion Polymer toward Maximizing mRNA Introduction Efficiency” on Macromolecular Rapid Communications has been introduced by EurekAlert!/AAAS.
▶ (04/05)EurekAlert！
11/28/2021
Professor Kazunori Kataoka, Director General of iCONM, has been selected to a 2021 Highly Cited Researcher in Clarivate Analytics (Web of Scinece), recognized for his exceptional research influence demonstrated by the production of multiple highly-cited papers that rank in the top 1% by citations for field and year in Web of Science.
▶List of 2021 Highly Cited Researchers
▶Researcher Page (Kazunori Kataoka)
10/12/2021
The Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, in collaboration with the Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, has succeeded in efficiently delivering an immune checkpoint inhibitor (ICI) into the mouse brain, confirming its high efficacy and specificality in treating orthotopically transplanted mice with glioblastoma (GBM), A press seminar was held.
▶Conjugation of glucosylated polymer chains to checkpoint-blockade antibodies augment their efficacy and specificity for glioblastoma
▶(10/06) Press Release
悪性脳腫瘍の中で特異的に活性化し、副作用なく治療を行う免疫チェックポイント阻害抗体の開発に成功
▶(10/11) EurekAlert!
Antibody delivery technology empowers immunotherapy against glioblastoma and suppresses side effects
▶(10/11) ScienMag
Antibody delivery technology empowers immunotherapy against glioblastoma and suppresses side effects
10/08/2021
Innovation Center of NanoMedicine in collaboration with the Chinese Academy of Science (CAS) Key Laboratory of Soft Matter Chemistry (USTC: University of Science and Technology), has created nanomachines that detect MMPs (matrix metalloproteinases), a principal enzyme for cancer cells to invade normal tissue, and deliver anticancer drugs according to an announcement in the journal Advanced Materials (IF = 30.849).
▶Enzymatically transformable polymersome-based nanotherapeutics to eliminate minimal relapsable cancer
▶(10/08) Press Release
手術後の浸潤性の高いがんを検出し再発を予防する高分子ナノソームの創出〜がんの転移・再発の予防
▶(10/13) Mirage News
Creating smart nanomachines to detect highly invasive cancer after surgery and prevent recurrence - cancer metastasis and recurrence
▶(10/12) EurekAlert!
Creating smart nanomachines to detect highly invasive cancer after surgery and prevent recurrence - cancer metastasis and recurrence prevention
08/11/2021
An article about our research "Nano-micelle Packaging CRISPR/Cas9 Components Enables Brain Genome Editing” was posted on TriLink BYOTECHNOLOGIES.
▶ (07/20) TriLink BYOTECHNOLOGIES
CleanCapR IVT Cas9 mRNA in Micelles Used for Genome Editing in Mouse Brain for the First Time
08/04/2021
An Article of JST NEWS (published on June) was published in Science Japan website.
▶ (08/04) Early Detection and Treatment Facilitated Using Nanomachines: Guaranteed Health
08/03/2021
Innovation Center of NanoMedicine and the International University of Catalunya jointly announced that Polymeric Nanomicelles Improve Internalization of Lipid Metabolism Modulators in Brain Cells.
▶ Press release
▶ (08/03) EurekAlert!
▶ (08/04) Pharm Tech Japan Online
▶ (08/04) 医薬通信社 (Japanese)
▶ (08/05) 日本の研究.com (Japanese)
▶ (08/11) 日刊工業新聞電子版 (Japanese)
▶ (08/16) 化学工業日報 4 面
iCONM - カタルーニャ国際大 脂質代謝を抑制 薬物送達技術を開発 (Japanese)
▶ (09/03) AZO NANO
07/26/2021
Dr. Yasutaka ANRAKU (Project Associate Professor, Dept. of Bioengineering, Graduate School of Engineering, The University of Tokyo) was appeared NHK World “Medical Frontiers” and explained nanomachines with the ability to deliver drug into the brain.
▶ (NHK World) Tackling Dementia After Onset
07/15/2021
An article about the press release on 4/20 "Treatment of primary and metastatic breast and pancreatic tumors upon intravenous delivery of a PRDM14-specific chimeric siRNA/nanocarrier complex" was published in Science Japan.
▶ (07/15) Development of innovative nucleic acid drugs effective against refractory breast and pancreatic cancers
07/02/2021
An Article of JST NEWS (published on June) was published in 客観日本 website.
▶ (07/02) “纳米机器”开拓新医疗方式，通过早期发现和治疗实现人人健康的社会 (Chinese)
02/18/2021
COINS received the Japan Open Innovation Prize (JOIP) Selection Committee Special Award.An article on this subject was published in the media.
▶ Press Release
▶ Japan Open Innovation Prize (JOIP) (Cabinet Office website)
▶ Click here for award winners (Cabinet Office website)
▶ (02/19) 医薬通信社
02/18/2021
Dr. Kazunori Kataoka (Principal Research Scientist／Laboratory Head)'s joint research group of Innovation Center of NanoMedicine developed functional nano-micelles with optimal drug release depending on the c-Myc expression level. This was collaborative research with Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo (Professor: Tatsuya YAMASOBA) Research group of Dr. Yu MATSUMOTO and Department of Bioengineering, Graduate School of Engineering the University of Tokyo (Head: Ryo MIYAKE) Research group of Dr. Horacio CABRAL. A press seminar was held.
▶ Press Release
▶ Press conference
▶ Efficacy of pH-sensitive nanomedicines in tumors with different c-MYC expression depends on the intratumoral activation profile
2021/02/12
February 10 (Wed.), KAWASAKI coastal area PR video has been released by Kawasaki city. In this video, iCONM is highlighted as the core institution of King Skyfront. Please watch the video for details.

▶ Press Release
12/02/2020
Prof. Kazunori Kataoka, Director General of iCONM, received the " KOSÉ -Cosmetology Encouragement Award" launched this year by the KOSÉ Cosmetology Research Foundation. This award recognizes researchers who have made achievements in the development of cosmetology research through the publications of their research papers based on the research grant provided by the foundation. Among the researchers who received the grants from 1990, when the foundation was established, to 2017, three researchers who were recognized as having outstanding achievements in the development of Cosmetology by investigating the results of their dissertations were commended.
11/18/2020
Professor Kazunori Kataoka, Director General of iCONM, has been selected to a 2020 Highly Cited Researcher in Clarivate Analytics (Web of Scinece), recognized for his exceptional research influence demonstrated by the production of multiple highly-cited papers that rank in the top 1% by citations for field and year in Web of Science.
▶ List of 2020 Highly Cited Researchers
11/12/2020
Dr. Kazunori Kataoka (Principal Research Scientist／Laboratory Head)'s joint research group of Innovation Center of NanoMedicine (iCONM) demonstrated a Therapeutic Option for Glioblastoma using pH-Sensitive Nanomicelles in a collaboration study with the Department of Bioengineering, Graduate School of Engineering, The University of Tokyo.
▶ More info
▶ Press Release
▶ Supramolecularly enabled pH- triggered drug action at tumor microenvironment potentiates nanomedicine efficacy against glioblastoma
09/08/2020
Dr. Sabina Quadar (Senior Research Scientist) interviewed a scientific media "Neuro-Central" together with Dr. Rosalia Rodoriguez-Rodoriguez (Department of Basic Sciences, Associate Professor, University of Catalonia, Spain), who is the co-corresponding author of a review article (title: An overview of nanomedicines for neuron targeting) published in Nanomedicine, Vol. 15 (6) on July 3, this year, and the interview article was published on September 2.
▶ (09/02) Neuro-Central
A peek behind the paper - Sabina Quader and Rosalia Rodriguez-Rodriguez on nanomedicines for neuron targeting
▶ More info
08/21/2020
Our paper entitled "Targeting nanoparticles to the brain by exploiting the blood-brain barrier impermeability to selectively label the brain endothelium" has been published online on PNAS, Proc. Natl. Acad. Sci. USA.
▶ (07/27) BioWorld Science
NP strategy selectively targets brain microvasculature (You must log in to see this content)
06/26/2020
For the first time in the world, Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine has succeeded in controlling the clearance of gene therapy drugs at the liver sinusoidal wall by developing a reagent for the selective and transient coating of the liver sinusoidal walls. This was collaborative research with the National Institute for Quantum Science and Technology and Department of Bioengineering, Graduate School of Engineering, The University of Tokyo. A press conference was held.
▶ Press conference
▶ Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines.
06/05/2020
Dr. Kazunori Kataoka (Principal Research Scientist／Laboratory Head)'s joint research group of Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion including the Tokyo Metropolitan Institute of Medical Science started collaborative research on April 1st 2020. It aims to create technology for the rapid development of mRNA vaccine integrated with an adjuvant function to be prepared for the recurrence of the new coronavirus (covid-19), and /or further mutated species of “coronavirus”.
▶ Press conference
05/22/2020
Dr. Kazunori Kataoka (Principal Research Scientist／Laboratory Head)'s joint research group of Innovation Center of NanoMedicine (iCONM) including Dr. Yasutaka Anraku Visiting Research Scientist (University of Tokyo, Cabral Lab.) and their research group designed and synthesized smart nanomachine® that efficiently deliver antibody drugs into the brain and succeeded in demonstrating the suppression of amyloid β aggregation in brain parenchyma at low doses in Alzheimer-type dementia model mice, and a joint press conference was held.
▶ Dual-sensitive nanomicelles enhancing systemic delivery of therapeutically active antibodies specifically into the brain
▶ Press conference
▶ (05/27) Nikkei Beyond Health (Japanese)
▶ (05/22) Faculty of Engineering, The University of Tokyo Press Releases
▶ (05/22) School of Engineering, The University of Tokyo Press Releases
▶ (05/21) Japan Agency for Medical Research and Development (Japanese)
05/22/2020
Dr. Kazunori Kataoka (Principal Research Scientist／Laboratory Head)'s joint research group of Innovation Center of NanoMedicine (iCONM) including Dr. Takuya Miyazaki Visiting Research Scientist (KISTEC), Dr. Horacio Cabral Visiting Research Scientist (University of Tokyo), Dr. Takeshi Nagamatsu (University of Tokyo) and Dr. Kensuke Suzuki (University of Tokyo), have developed nanomedicine for chemotherapy during pregnancy. With this nanomedicine, we can treat intractable diseases like preeclampsia and preterm birth without drug distribution in fetus.
▶ (05/12)The Society of Polymer Science Press Release
05/22/2020
About the research on smart NanoMachines and in-body hospitals at iCONM was carried on article of Deutsche Well.
▶ (04/28)Deutsche Well
COVID-19: Nanomachines to be deployed to fight next viral pandemic
11/26
Ms. Noriko Nakamura (D2 The University of Tokyo, Cabral Lab.) received the JSB Outstanding Poster Award 2019 at the 41st Annual Meeting of the Japanese Society for Biomaterials (Ibaraki, Japan). The presentation title is "Interaction analysis between target membrane proteins and ligand molecules attached to the polymeric micelle with different molecular weight of hydrophilic shell" (Coauthers: Yasutaka Anraku, Shigeto Fukushima, Kazuko Tou, Horacio Cabral, Kazunori Kataoka).
11/22
Professor Kazunori Kataoka, Director General of iCONM, has been selected to a 2019 Highly Cited Researcher in Clarivate Analytics (Web of Scinece), recognized for his exceptional research influence demonstrated by the production of multiple highly-cited papers that rank in the top 1% by citations for field and year in Web of Science.
11/08
Our paper entitled "ingle-stranded DNA-packaged polyplex micelle as adeno-associated-virus-inspired compact vector to systemically target stroma-rich pancreatic cancer" has been published online on ACS Nano.
▶ Press conference
06/28
Mr. Takuya Nishizono (M2: The University of Tokyo, Cabral Lab.) received the best poster award at 68th SPSJ Annual Meeting. The presentation title is "Evaluation on brain accumulation and distribution of nanocarriers with different sizes" (Coauthers: Yu Fukusato, Noriko Nakamura, Kazuko Toh, Horacio Cabral, Yasutaka Anraku, Kataoka Kataoka).
06/28
Mr. Yoshihiro Tachihara (D1: The University of Tokyo, Cabral Lab.) received the best poster award at 68th SPSJ Annual Meeting. The presentation title is "Development of pH-Sensitive Polymeric Micelles for Targeted Delivery of the Macrocycle Valinomycin via Host Guest Interaction" (Coauthers: Miyazaki Takuya, Quader Sabina, Nakagawa Yasuhiro, Anraku Yasutaka, Kataoka Kazunori and Cabral Horacio).
05/30
Professor Kazunori Kataoka, Director General of iCONM, was installed as an Honorary Member of the Society of Polymer Science, Japan.
04/26
Our paper entitled "In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancer" has been published online on Nature Communications.
▶ (04/23) Alpha Galileo
New nanomedicine slips through the cracks - Nanomachines aim to deliver cancer drugs to hard-to-reach areas like the brain
▶ (04/24) EurekAlert
New nanomedicine slips through the cracks
▶ (04/24) UTokyo Focus
New nanomedicine slips through the cracks Nanomachines aim to deliver cancer drugs to hard-to-reach areas like the brain
▶ (04/24) Nanowerk
New nanomedicine slips through the cracks
▶ (04/24) ecancer
New nanomedicine slips through the cracks
▶ (04/24) Phys.org
New nanomedicine slips through the cracks
▶ (04/24) Science Daily
New nanomedicine slips through the cracks, reaches brain: Nanomachines aim to deliver cancer drugs to hard-to-reach areas like the brain
03/02
Ms. Noriko Nakamura (D1: The University of Tokyo, Cabral Lab.) received the TEIJIN Prize at the TEIJIN MIRAI FORUM 2019. The presentation title is "Interaction between ligand molecules on the drug delivery carrier penetrating blood-brain barrier and targeting membrane proteins" (Coauthers: Y. Anraku, S. Fukushima, K. Toh, H. Cabral, K. Kataoka).
01/23
Interview about Prof. Kazunori Kataoka, Director General of iCONM, was carried on article of btcn asia.
▶ (1/21) Part 1: Nanomedicine in neurodegenerative diseases like Alzheimer’s
▶ (1/28) Part 2: The future of nanomedicine for everybody
12.21
Dr. Beob Soo Kim Visiting Research Scientist (The University of Tokyo, Miyata Lab.) has received Poster Award: Polymers Award at the IPC2018. The presentation title is "Vesicular self-assemblies from siRNAs and PEGylated block catiomers (siRNAsomes): Their structural, physicochemical, and biological characteristics" (Coauthers: Kanjiro Miyata, Akihiro Kishimura, Kazunori Kataoka).
12.15
Dr. Hyun Jin Kim Visiting Research Scientist (The University of Tokyo, Miyata Lab.) has received Best Poster Award at the 5th COINS Symposium. The presentation title is "Development of Amphiphilic Polymers for Cas9 mRNA Delivery" (Coauthers: Kazunori Kataoka, Kanjiro Miyata).
11.29
Prof. Kazunori Kataoka, Director General of iCONM, has been named a 2018 Highly Cited Researcher in Clarivate Analytics (Web of Science) meaning that research ranks among the top 1% most cited works in the corresponding field.
11.24
Feature article of "In-body hospitals" which is the core theme of iCONM / COINS was published in Nature.
Following Dr. Kazunori Kataoka's interview article, the efforts of iCONM / COINS, National Cancer Research Center East Hospital, Tokyo Women's Medical University, Braizon Therapeutics and Quantum Science and Technology Research and Development organization are introduced.
▶ (11/15)nature
Nanomedicine in Japan
10.20
The article "Enhanced intracellular delivery of siRNA by controlling ATP-responsivity of phenylboronic acid-functionalized polyion complex micelles", published in Macromolecular Bioscience, was one of the journal's top 20 most downloaded recent papers amongst articles published between July 2016 and June 2018.
09.02
Dr. Kazunori Kataoka, Director General of Innovation Center of NanoMedicine (iCONM)/ Research Leader of Center of Open Innovation Network for Smart Health (COINS) was awarded the honorary doctorate (Doktor der Naturwissenshaften ehrenhalber; Dr. rer. Nat. H. C.) from Johannes Gutenberg University (Mainz University) in Germany.
The honorary doctorate of Mainz University is awarded to researchers who have globally achieved exceptionally high level of performance. This time, Dr. Kataoka's research titled "Development of Polymer Therapeutics and Their Application to Cancer Treatment" was highly appreciated in the Faculty of "Chemistry, Pharmaceutical Science and Earth Sciences" and it was the first time in eight years for the Faculty to be awarded.
The award ceremony was held at Mainz University in August 31, and a commemorative symposium was held at the same time. (Click here for the details)
▶ Program
01.28
Professor Kazunori Kataoka became Associate Editor of ACS Nano published by American Chemical Society.
12.21
Prof. Kazunori Kataoka received "Princess Takamatsu Cancer Research Fund Prize" of 2017 for his pioneering research on "The Development and Clinical Translation of Delivery Systems of Anti-Cancer Reagents based on Polymeric Micelles".
12.17
Professor Kazunori Kataoka, Director General of the Innovation Center of NanoMedicine, has been elected to a Fellow of the National Academy of Inventors (NAI). Election to NAI fellow status is the highest professional accolade bestowed solely to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society.
On April 5. 2018, the 2017 NAI Fellows will be inducted as part of the Seventh Annual NAI Conference of the National Academy of Inventors at the Mayflower Hotel, Autograph Collection in Washington, D.C. Andrew H. Hirshfeld, the U.S. commissioner for patents, will provide the keynote address for the induction ceremony.
▶ Complete list of NAI Fellows
12.08
▶ COINS will hold the 4th COINS Symposium.
Date: Dec. 8（Fri.）10:00〜(Registration starts at 9:30am)
Venue: Ground Floor & 4th Floor, Public Interest Incorporated Foundation, Kawasaki Institute of Industrial Promotion, Kawasaki City Industrial Promotion Hall
Language: Japanese & English
Registration Fee: Free
The symposium website
11.29
Prof. Kazunori Kataoka received John G. Wagner Memorial Lectureship Award from College of Pharmacy, the University of Michigan, and gave the Memorial Lecture.
▶ 22nd Annual John G. Wagner Memorial Lecture
11.18
Prof. Kazunori Kataoka, Director General of iCONM, has been named a 2017 Highly Cited Researcher in Web of Science, meaning that research ranks among the top 1% most cited works in the corresponding field.
10.18
Our paper entitled "Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain" has been published online on Nature Communications.
▶ (10/18) The Nikkei Online
▶ (10/19) The University of Tokyo Press Releases, School of Engineering The University of Tokyo Press Releases, Japan Science and Technology Agency
▶ (10/20) The University of Tokyo Press Releases Facebook, Kanagawa Shimbun, Yahoo!JAPAN News, Nikkan Kogyo Shimbun Online, Med IT Tech
▶ (10/23) QLifePro
10.12
Our paper entitled "Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly a sequences for effective vaccination" has been published online on Biomaterials.
▶ (10/12) The University of Tokyo Press Releases, School of Engineering The University of Tokyo Press Releases, The University of Tokyo Press Releases (Facebook)
Jiji Press, Jiji Medical, Nikkan Kogyo Shimbun Online, Yahoo!JAPAN News, Infoseek Rakuten News
▶ (10/16) QLifePro
07.31
Comment about our Director General, Dr. Kazunori Kataoka was carried on article of Sumitomo Corporation.
▶ Sumisho Scrum LIVE REPORTS Vol.3 Ensuring Japan's Future through Support for the Pharmaceutical Industry.
06.23
Angewandte Chemie International Edition (Published by German Chemical Society) published a news on June 268 describing the election of Prof. Kazunori Kataoka, Director General of iCONM, to Foreign Member of United States National Academy of Engineering.
News: New Members and Foreign Members of the National Academy of Engineering
06.02
Dr. Kanjiro Miyata, Visiting Research Scientist (The University of Tokyo, Miyata Lab.) has received The Nucleic Acids Therapeutics Society of Japan (NatsJ) Award for Young Scientists.
04.14
Our Director General, Dr. Kazunori Kataoka is awarded to the 34th H. C. Brown Lecturer at Purdue University, USA. This Lectureship is named after the famous organic chemist, Prof. H. C. Brown (1979 Noble Laureate in Chemistry), and is recognized as a great honor in the field of organic chemistry.
▶ 34th Annual H.C. Brown Lectures - April 14, 2017
04.12
Dr. Yasutaka Anraku, Visiting Research Scientist (The University of Tokyo, Cabral Lab.） was awarded The Young Scientist's Prize for The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology.
03.23
Our article "A facile amino-functionalization of poly(2-oxazoline)s' distal end through sequential azido end-capping and Staudinger reaction" (Volume 88, March 2017, Pages 553-561) published in European polymer journal was highlighted on Advances in Engineering.
▶ Advances in Engineering
03.15
Dr. John Daniel MARTIN (Visiting Researcher, JSPS Postdoctoral Fellow@Cabral Lab, The University of Tokyo) and Dr. Sam CROWLEY (Research Scientist) received the Presentation of Poster Awards at the 11th Annual Symposium on Nanobiotechnology 2017 . Title is "Proteasome inhibitor loaded micelles enhance antitumor activity through macrophage reprograming by NF-κB inhibition" (John Daniel MARTIN), "BDNF mRNA Injection Improves Recovery Following Spinal Cord Injury in Mice" (Sam CROWLEY).
03.01
Mr. Daiki Sueyoshi (D3: Cabral Lab, The University of Tokyo) received the Dean Award for Academic Excellence from Graduate school of Engineering, The University of Tokyo.
02.09
Dr. Kazunori Kataoka, Director Generel of iCONM, has been elected to a Foreign Member of the United States National Academy of Engineering (NAE) for his pioneering contributions to the design of supramolecular nanostructures and their application to drug and gene delivery systems.
▶ National Academy of Engineering Elects 84 Members and 22 Foreign Members
▶ National Academy of Engineering (NAE)/Wikipedia
▶ The University of Tokyo
▶ School of Engineering The University of Tokyo Press Releases
▶ The University of Tokyo Facebook
01.31
Dr. Yasutaka Anraku (Visiting Researcher, Assistant Professor@Cabral Lab, The University of Tokyo) received the Takagi award at the 26th Inteligent Materials/Systems Symposium. Title is "Development of Innovative Therapeutic Polymeric Micelles for Intractable Neurological Disease".
01.30
Special Issue: Dedicated to Kazunori Kataoka on the Occasion of his 65th Birthday has been published in Macromolecular Bioscience (Wiley-VCH) as Volume 17, Issue 1, 2017. This issue was dedicated to Professor Kazunori Kataoka for celebrating his 65th birthday, and highlights his pioneering work in nanomedicine with great contributions in polymer chemistry, supramolecular chemistry, biomaterials, drug and gene delivery. The special issue was edited by Dr. Horacio CABRAL, Dr. Kanjiro MIYATA, and Dr. Kensuke OSADA, who received great edification from Prof. Kazunori Kataoka. All the articles in this issue are free to view online until end of 2017.
▶ Macromolecular Bioscience (Wiley-VCH) as Volume 17, Issue 1
01.18
Peng Mi Senior Research Scientist entitled "Molecular cancer imaging with polymeric nanoassemblies: From tumor detection to theranostics" has been published on Macromolecular Bioscience (Volume 17, Issue 1, Special Issue: Dedicated to Kazunori Kataoka on the Occasion of his 65th Birthday) and selected as a cover picture.
▶ Paper / Cover Picture
01.10
Mr. Daiki Sueyoshi (D3: Cabral Lab, The University of Tokyo) received the IPC2016 young scientist poster award at The 11th SPSJ International Polymer Conference (IPC2016). The presentation title is "Enzyme-Loaded Polyion Complex Vesicles as Intravital Reactors Functioning in Vivo in the Circulating Blood" (Coauthers: Yasutaka Anraku, Kazunori Kataoka).
01.04
iCONM will hold the 11th Annual Symposium on Nanobiotechnology
Date: Feb. 27 (Mon.) & 28 (Tue.) 9:30am -(Registration starts at 8:30am)
Venue: Ground Floor & 4th Floor, Public Interest Incorporated Foundation, Kawasaki Institute of Industrial Promotion, Kawasaki City Industrial Promotion Hall
Language: English (No simultaneous interpretation)
Registration Fee: 3,000yen ※ Please register online.
The symposium website can be found here.
12.20
Our article "A membrane-integrated microfluidic device to study permeation of nanoparticles through straight micropores toward rational design of nanomedicines" just published in Analytical Sciences has been selected by the Hot Article.
12.08
Our article "Targeting the notch-regulated non-coding RNA TUG1 for glioma treatment" just published in Nature Communications was highlighted on Japan Agency for Medical Research and Development (AMED) and Nagoya University.
▶ Japan Agency for Medical Research and Development (AMED) Press Release (Japanese)
▶ Nagoya University Press Release (Japanese)
▶ Nagoya City University Press Release (PDF/Japanese)
12.08
Our article "Poly(ethylene glycol) crowding as critical factor to determine pDNA packaging scheme into polyplex micelles for enhanced gene expression" just published in Biomacromolecules has been selected to be featured in the ACS Editors' Choice based on recommendations by the scientific editors of ACS journals from around the world.
11.02
Principal Research Scientist Keiji Itaka (Itaka Lab) received The 4th International mRNA Conference Best Poster Awards and Best Abstract Presentations award.The presentation title is "Intracerebral administration of mRNA for treating brain diseases: An animal study for augmenting clearance of beta-amyloid using neprilysin mRNA" (Co-author: C.-Y. Lin, S. Uchida, K. Kataoka)
07.28
Our article "Nanomedicines eradicating cancer stem-like cells in vivo by pH-triggered intracellular cooperative action of loaded drugs" published in ACS Nano was highlighted on i-newsletter (Vol.7, July 2016).
▶ Kawasaki SkyFront i-newsletter (Vol.7, July 2016)
07.06
Visiting Scientist Satoshi Uchida (Itaka Lab) received the japanese and korean biomaterials societies young scientist exchange program award (2016). The presentation title is "Development of messenger RNA-loaded polyplex nanomicelle for the treatment of central nervous system diseases" (Co-author: Yuta Fukushima, Chin-Yu Lin, Keiji Itaka, Kazunori Kataoka).
07.04
Our article "Nanomedicines Eradicating Cancer Stem-like Cells in Vivo by pH-Triggered Intracellular Cooperative Action of Loaded Drugs" published in ACS Nano is the top Most Read Article from the journal's Top 20 most downloaded articles for the previous month.
▶ ACS Nano Most Read Articles
06.07
Our article "A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy" just published in Nature Nanotechnology was highlighted on Nanotechweb.org, Phys.org and more.
▶ (6/10) Tokyo Tech News (Tokyo Institute of Technology)
"Nanomachine Contrast Agent" using existing MRI detects minimal cancer tissue with a highly sensitive visualization
▶ (6/6) Phys.org
New nanoparticle-based contrast agent that is pH dependent
▶ (6/6) Nanotechweb.org
pH-sensitive nanoparticles detect millimetre-sized tumours
06.06
"Medical Frontiers" will broadcast on June 14 (00:30～、06:30～、12:30～、18:30～), at NHK World.
▶ NHK WORLD TV Live Page
▶ NHK On-Demand (Between the broadcast date of 2 weeks)
06.06
Our article "Nanomedicines Eradicating Cancer Stem-like Cells in Vivo by pH-Triggered Intracellular Cooperative Action of Loaded Drugs" just published in ACS Nano was highlighted on "Cancer stem cell news".
06.01
Our article "Nanomedicines Eradicating Cancer Stem-like Cells in Vivo by pH-Triggered Intracellular Cooperative Action of Loaded Drugs" just published in ACS Nano has been selected to be featured in the ACS Editors' Choice based on recommendations by the scientific editors of ACS journals from around the world.
The ACS Editor's Choice selects one new peer-reviewed research article from any ACS journal to be freely available, and remain open for all to access and read.
05.17
Our paper entitled "A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy" has been published online on Nature Nanotechnology, and was carried on
(5/19) NEWS QLifePro, (5/18) Nikkei Digital Health, Web【＠MED】, Gunosy(5/17) The University of Tokyo Press Releases (Facebook), (Twitter), School of Engineering The University of Tokyo Press Releases, National Institutes for Quantum and Radiological Science and Technology, Jiji Press, Kanagawa Shimbun, Nikkei Press Release, Nikkan Kogyo Shimbun Online, Asahi Shimbun Digital, Asahi Shimbun Digital Apital, Mynavi, innavi net, innavi net (2)
04.27
Our paper entitled "Calcium phosphate-based organic-inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy" has been published on Biomaterials Science (Volume 4, Issue 5, 826-838 May 2016) and selected as a Inside front cover.
▶ Paper / Inside front cover
04.25
Our paper entitled "Nanomedicines Eradicating Cancer Stem-Like Cells in Vivo by pH-Triggered Intracellular Cooperative Action of Loaded Drugs" has been published online on ACS Nano, and was carried on The University of Tokyo Press Releases, The University of Tokyo Facebook, The University of Tokyo Twitter, (4/20) Nikkei Sangyo Shimbun, (4/19) The Chemical Daily, (4/19) Kanagawa Shimbun, (4/19) Nikkan Kogyo Shimbun, (4/19) Nikkan Kogyo Shimbun Online, (4/18) TV Kanagawa (tvk) NEWS930α, (4/18) Nikkei Press Release, (4/18) TVK News, (4/18) Yahoo!Japan News
04.01
Prof. Kataoka became Specially-appointed Professor of Policy Alternative Research Institute, the University of Tokyo, and is appointed to Director General of Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industry Promotion, Kawasaki, Japan.
▶ Innovation Center of NanoMedicine (iCONM) homepage
▶ The Policy Alternatives Research Institute
03.29
News about Prof. Kataoka was carried on University of North Carolina homepage.
▶ Inaugural Carolina Nanoformulation Workshop Shares Discoveries in Nanomedicine
03.17
Our paper entitled "Influence of RNA strand rigidity on polyion complex formation with block catiomers" has been published on Macromolecular Rapid Communications (Volume 37, Issue 6, 486-493 March 2016) and selected as a back cover.
▶ Paper / Back Cover
03.02
Our paper entitled "Rod-to-globule transition of pDNA/PEG-Poly(L-lysine) polyplex micelles induced by a collapsed balance between DNA rigidity and PEG crowdedness" has been published on Small (Volume 12, no. 9, March 2, 2016) and selected as a back cover.
▶ Paper / Back Cover
02.29
The paper entitled "Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery" was published in Nature Nanotechnology, and was carried on nanotechweb.org and UroToday.
▶ nanotechweb.org (2/22)
Tumour blood vessel defects amass large nanoparticles
▶ UroToday (2/23)
Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release
02.16
The paper entitled "Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery" from our lab is published in Nature Nanotechnology, and is featured in News & Views of the Issue.
▶Drug delivery: Redefining tumour vascular barriers
02.09
Our paper entitled "Intracellular delivery of charge-converted monoclonal antibodies by combinatorial design of block/homo polyion complex micelles" has been published on Biomacromolecules (Volume 17, Issue 2, February 8, 2016) and selected as a cover.
▶ Paper / Cover
01.06
The paper entitled "Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment" was published in Scientific Reports, and was carried on The Nikkei(1/10)、The University of Tokyo、UTokyo Research(1/13)、The Nikkei(1/6)、JIJIPRESS、Toyo Keizai ONLINE、Yahoo! Japan、Mynavi News、Wall Street Journal、BIGLOBE News、Gadget News.
01.04
Associate Professor Kanjiro Miyata moved to Department of Materials Engineering on January 1.
11.16
Associate Professor Keiji Itaka received the best poster award at 3rd International mRNA Health Conference. The presentation title is "A disease-modifying strategy for osteoarthritis treatment by introducing mRNA encoding cartilage-anabolic transcription factor".
10.28
The paper entitled "Hybrid calcium phosphate-polymeric micelles incorporating gadolinium chelates for imaging-guided gadolinium neutron capture tumor therapy" from our lab that was published in ACS Nano, was featured in Phys.org.
Phys.org: Gadolinium-based particles show and treat tumours
10.14
Professor Kazunori Kataoka received "Advanced Materials Award 2015" from International Association of Advanced Materials (IAAM). Award ceremony and award lecture were held at Stockholm, Sweden on August 24, 2015.
10.01
The paper entitled "Induction of secondary structure through micellization of an oppositely charged pair of homochiral block- and homopolypeptides in an aqueous medium" from our lab that was published in Macromolecular Rapid Communications, was featured in MaterialsView.
MaterialsView: Understanding higher-ordered structures in polypeptides
09.07
News about Paclitaxel-loaded polymeric micelle was carried on NIKKEI ASIAN REVIEW.
Japanese cancer drug employing new tech could get green light soon
09.07
Paclitaxel-loaded polymeric micelle achieved successful results in clinical trials, and has been decided to proceed into application for approval in the fiscal year of 2015 by Nippon Kayaku Co. This is the first achievement from COINS project proceeding into the application for approval.
08.26
Innovation Center of Nanomedicine (iCONM) was featured in "A corner of analyze advance research center" in Nikkei Sangyo Shimbun on Aug. 19, 2015. The title is "Innovation Center of Nanomedicine Application of capsule - Industry-academic-gervernment collaboration."
08.26
"Nanomachines" being developed by Kataoka lab. was introduced in "A corner of the life expectancy increases up to 1000 years of age" in a monthly international communication periodical SAPIO September issue. The title is "Cancer treatment - Deliver drug directly by targeting cancer cell alone - Power of smart nanomachines of a virus size."
08.18
News about Gutenberg Research Award given to Prof. Kazunori Kataoka was published in August 4, 2015 Issue of Angewandte Chmie International Edition, the official scientific journal of German Chemical Society.
▶ 2015 - Prof. Kazunori Kataoka and Prof. Kwok Pui Lan
▶ ChemistryOpen：Gutenberg Research Award Goes to Kataoka
▶ ChemMedChem：Kazunori Kataoka Receives Gutenberg Research Award
▶ YouTube: Gutenberg Research College welcomes new members and bestows the 2015 Gutenberg Research Award
06.15
The paper entitled "Hybrid calcium phosphate-polymeric micelles incorporating gadolinium chelates for imaging-guided gadolinium neutron capture tumor therapy" from our lab was published in ACS Nano, and was carried on Yahoo JAPAN News、Woman excite、Nikkei BioTech ONLINE、Mynavi News、livedoor NEWS、YOMIURI News & Weather、Nikkan Kogyo Shimbun、Nittele NEWS24、TV-Asahi news、Kagaku Shimbun、Asahi Shimbun、Yomiuri Shimbun、NHK NEWS WEB.
06.04
Research project on "Polymer Nanomachine" has been carried on "METI Journal" (PDF:Japanese) published from Ministry of Economics, Technology, and Industry, Japan"
06.03
Professor Kataoka and his group's achievements in nanomedicine for cancer treatment was highlighted on "Scientific American".
05.11
Newly opened "Innovation Center of NanoMedicine (iCONM)" at KingSky Font of Kawasaki-city was broadcasted on May 9, 2015 at TV Kanagawa (TVK).
05.11
Prof. Kazunori Kataoka received the Gutenberg Research Award 2015.
External links: Prof. Kazunori Kataoka
2015 - Prof. Kazunori Kataoka and Prof. Kwok Pui Lan
05.11
Prof. Kazunori Kataoka was awarded from School of Pharmacy, University of Wisconsin-Madison to have 2015 Louis W. Busse Lectures on April 30 and May 1, 2015. (JPG)
04.30
The paper entitled "Systemic targeting of lymph node metastasis through the blood vascular system by using size-controlled nanocarriers" from our lab was published in ACS Nano, and was carried on The University of Tokyo, UTokyo Research, Nikkan Kogyo Shimbun, etc.
04.08
Prof. Kataoka will appear on the news program of TV (BS Nippon TV) at 10pm (Japanese time) on April 14, 2015, explaining the recent achievements of his research on nanomachines (polymeric micelles).
04.08
Achievements of FIRST project led by Prof. Kataoka and funded by Japanese Government have been carried on The Science News on April, 3, 2015.
03.26
Our paper entitled "A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle" has been published on Soft Matter (Volume 11, Issue 14, 2718-2722, 2015) and selected as a cover.(Cover・Paper)
03.23
The article (H. J. Kim, et al, Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer, Drug Delivery and Translational Research (2014) 4:50-60) from Kataoka lab. was selected as the 2014 DDTR Outstanding Research Paper Award. Award Lecture will be given by Dr. Kanjiro Miyata, representing all the co-authors of this article, at the 2015 Controlled Release Society Annual Meeting in Edinburgh, Scotland during July 26-29, 2015.
03.16
The research on Nanomachine ongoing at Kataoka laboratory was broadcasted on March 13 in the TV program "Innovationism" at BS Fuji.
02.09
Articles on messenger RNA (mRNA)-loaded nanomachine for treating neurological disorders as a new system of gene therapy: JIJI Press, Nikkei Biotech online, Nikkan Kogyo Shimbun, The Wall Street Journal, Nikkei Sangyo Shimbun, UTokyo Research, JST Science Portal, AsianScientist.
01.26
Prof. Kazunori Kataoka received Gutenberg Research Award from Johannes Gutenberg University Mainz. The Award ceremony will be take place in Mainz on May 4, 2015.
01.13
Interview to Prof. Kataoka regarding his research on supramolecular nanomachines for medical use was carried on the newspaper, Kagaku Kogyo Nippo on Jaunuary 5, 2015.
01.05
The research on Nanomachine ongoing in our laboratory was broadcasted by NHK on January 4 in the TV program "NEXT WORLD - Our Future".
12.30
Clinical trials on breast cancer by the use of siRNA delivery system developed at Kataoka Lab will be started within this fiscal year at the Research Hospital, the Institute of Medical Science, the University of Tokyo by the team of Prof. Kozo Imai.
12.24
Article on the polymeric micellar drugs developing at Kataoka Laboratory, University of Tokyo was appeared in the scientific column of the evening edition of Yomiuri Shimbun (Yomiuri Newspaper) on December 18.
12.08
Mr. Mitsuru Naito (D3) received the IPC2014 young scientist poster award at The 10th SPSJ International Polymer Conference (IPC2014). The presentation title is "Cholesterol-modified siRNA Loaded Stimuli-responsive Polyion Complex Micelle for Smart siRNA Delivery" (Coauthers: T. Ishii, A. Matsumoto, K. Miyata, Y. Miyahara and K. Kataoka).
11.17
Dr. Yuuki MOCHIDA received the Best Presentation Award at The 23rd Polymer Materials Forum. His presentation title is "Core-forming helix bundles enhances antitumor efficacy of cisplatin-loaded polymeric micelles constructed from PEG-poly(glutamic acid) block copolymers" (Coauthers：H. Cabral, Y. Miura, K. Osada, N. Nishiyama, K. Kataoka).
10.24
Research on the antibody delivery to brain crossing blood-brain barrier has been carried on Nikkei Industrial Newspaper on October 24, 2014.
10.23
Mr. Jun Makino (D3) received the Best Poster Award at the nanoDDS 12th international nanomedicine & drug delivery symposium. The presentation title is "Systemic targeting of lymph node metastasis by controlled design of drug-loaded polymeric micelles" (coauthers: H. Cabral, Y. Miura, Y. Matsumoto, H. Kinoh, N. Nishiyama, K. Kataoka).
10.07
Mr. Mizoguchi's presentation was selected as one of the highlighted presentations at the 36th Annual Meeting of the Japanese Society for Biomaterials. His presentation title is "Development of brain-targeting antibody by conjugating multi-glucose polymers". (coauthors: Akihiro Mizoguchi, Yasutaka Anraku, Yu Fukusato, Hiroya Kuwahara, Kazutaka Nishina, Takanori Yokota and Kazunori Kataoka)
09.10
Dr. Satoshi Uchida (Assistant Professor) received a Young Investigator Award at the Antisense, Gene, Delivery Symposium 2014. His presentation title is "Treatment of spinal cord injury by combinational system of non-viral gene introduction and spheroid transplantation" (Coauthors: K. Itaka, K. Hayakawa, T. Ogata, K. Kataoka).
08.04
Ms. Kayoko Yanagihara (D1) received the Best Presentation Award at the 30th Japan DDS Conference. The presentation title is "The application of mesenchymal stem cell spheroids to bone regeneration treatment: activation of cell functions by gene transfection using nanomicelles" (coauthers: S. Uchida, M. Ikegami, T. Endo, Y. Maeda, S. Ohba, U. -I. Chung, T. Ishii, K. Itaka and K. Kataoka).
07.28
Prof. Kazunori Kataoka received the Journal of Drug Targeting's 2014 Lifetime Achievement Award. This Award recognizes scientist who have made exceptional and sustained contributions to drug delivery and targeting.
06.23
Prof. Kazunori Kataoka has been selected as a Thomson Reuters Highly Cited Researcher.
06.18
Mr. Yu Fukusato (D2) received an Outstanding Poster Presentation Award for the Society of Polymer Science Japan (SPSJ) 63th Annual Meeting. His presentation title is "Development of polyion complex nano-machines for drug delivery toward neural system across blood-brain barrier" (Coauthors, Y. Anraku, A. Mizoguchi, T. Ishii, H. Kuwahara, T. Yokota, K. Kataoka).
05.26
Dr. Satoshi Uchida (Assistant Professor) received an Outstanding Poster Presentation Award for the American Society of Gene and Cell Therapy (ASGCT) 17th Annual Meeting. His presentation title is "Treatment of Spinal Cord Injury by Transplantation of BDNF-Transfected Mesenchymal Stem Cell Spheroids" (Coauthors, K. Itaka, K. Hayakawa, T. Ogata, K. Kataoka).
05.19
Prof. Kataoka received "SPSJ Award for Outstanding Achievement in Polymer Science and Technology" from Society of Polymer Science, Japan. The title of the Award is "Development and Application of Biofunctionality Polymers".
04.02
Our paper entitled “Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer” was published in Nature Communications.
03.24
Dr. Qixian Chen, Mr. Yuuki Mochida and Ms. Kaori Machitani received the Dean Award for Academic Excellence from Graduate school of Engineering, The University of Tokyo.
02.17
Prof. Kataoka introduced novel polymeric micellar drug for targeted therapy of intractable cancer in a TV broadcast "World Business Satellite" on February 14, 2014.
12.18
Nano-Bio FIRST symposium will hold on February 21, 24.
12.16
Dr. Satoshi Uchida was promoted to Project Assistant Professor. (Division of Clinical Biotechnology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo)
09.26
The paper entitled "Cyclic RGD-Linked Polymeric Micelles for Targeted Delivery of Platinum Anticancer Drugs to Glioblastoma through the Blood-Brain Tumor Barrier" from our lab was published in ACS Nano, and was carried on The University of Tokyo, Kyodo News, Nikkan Kogyo Shimbun, etc.
07.10
Assistant Professor Yasutaka Anraku received the received Japanese and Korean Biomaterials Societies Young Scientist Exchange Program Award (2013). He will present the research, "Development of Enzyme-loaded Polyion Complex Vesicles (PICsomes) for Enzyme/Prodrug Therapies" (coauthors: A. Kishimura, M. Kamiya, S. Tanaka, T. Nomoto, K. Tou, Y. Matsumoto, M. R. Kano, Y. Urano, N. Nishiyama and K. Kataoka), at Symposium 2013 of the Japanese Society for Biomaterials.
07.08
Assistant Professor Yasutaka Anraku received the received The Best Presentation Award at the 29th Japan DDS Conference. His presentation title is "Development of Enzyme-loaded Polyion Complex Vesicles (PICsomes) for Enzyme/Prodrug Therapies" (coauthors: A. Kishimura, M. Kamiya, S. Tanaka, T. Nomoto, K. Tou, Y. Matsumoto, M. R. Kano, Y. Urano, N. Nishiyama and K. Kataoka).
06.27
The paper entitled "Targeted therapy of spontaneous murine pancreatic tumors by polymeric micelles prolongs survival and prevents peritoneal metastasis" from our lab was published in Proceedings of the National Academy of Sciences of United States of America(PNAS), and was carried on The University of Tokyo, Asahi, Mainichi and Nihonkeizai Newspaper, 47news, etc.
06.18
Professor Kazunori Kataoka's work on polymeric micelles was carried on the column "Creating the Future" of Asahi Newspaper on June 17, 2013.
04.03
Mr. Hiroyasu Takemoto (D3) was promoted to assistant professor. (Polymer Chemistry Division, Chemical Resources Laboratory, Tokyo Institute of Technology)
04.01
Dr. Yasutaka Anraku was promoted to assistant professor. (Department of Materials Engineering, The University of Tokyo)
03.25
Dr. Sabina Quader received the ICBS2013 Poster Award (Journal Controled Release) at the 2nd International Conference on Biomaterials Science in Tsukuba -ICBS2013-. Her presentation title is "Intracellular delivery of proteasome inhibitor MG132 by using polymeric micelles for effective cancer therapy" (coauthers：S. Quader, H. Cabral, Y. Mochida, T. Ishii, N. Nishiyama, K. Kataoka).
03.25
Mr. Mitsuru Naito (D1) received the ICBS2013 Poster Award (Biomaterials Science) at the 2nd International Conference on Biomaterials Science in Tsukuba -ICBS2013-. His presentation title is "Phenylboronate Functionalized Polyion Complex Micelles as ATP-sensitive Smart Delivery System of siRNA" (coauthers：M. Naito, T. Ishii, A. Matsumoto, K. Miyata, Y. Miyahara, K. Kataoka).
03.18
Dr. Takehiko Ishii was promoted to project associate professor. (Department of Bioengineering, The University of Tokyo)
03.04
Dr. Akihiro Kishimura (Assistant Professor at Materials Engineering) became a associate professor at center for molecular systems Kyushu University. (Homepage Katayama Lab)
02.18
The press conference on the paper "In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle" for PLOS ONE was held at the University of Tokyo and Todai Research.
02.06
Mr. Peng Mi (D3) received Young Scientist Poster Award at The 16th International Symposium on Recent Advances in Drug Delivery Systems. His presentation title is “Pegylated polyanion hybrid calcium phosphate micellar MRI probe for in vivo noninvasive solid tumor diagnosis” (coauthors: D. Kokuryo, M. Kumagai, H. Cabral, I. Aoki, N. Nishiyama, K. Kataoka).
02.04
Project Assistant Professor Yutaka Miura was promoted to assistant professor at Division of Clinical Biotechnology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo.
01.15
Nano-Bio FIRST symposium will hold on March 5.
01.09
Dr. Nishiyama (Associate Professor at Medical School) became a professor at Polymer Chemistry Division, Chemical Resources Laboratory, Tokyo Institute of Technology. (Homepage)
01.09
Assistant professor Kanjiro Miyata was promoted to associate professor at Division of Clinical Biotechnology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo.
12.19
Mr. Hiroyuki Chaya (M2) received the Best Poster Award at The 9th SPSJ International Polymer Conference (IPC 2012). His presentation title is "Design of PEGylated polyion complexes featuring single siRNA molecule ~Effect of chain lengths of PEG-b-polycations on the complex structure and properties~" (coauthers：S. Watanabe, H. Takemoto, S. Fukushima, K. Miyata, K. Osada, N. Nishiyama and K. Kataoka).
12.19
Ms. Mao Hori (B4) received the IPC2012 young scientist poster award at The 9th SPSJ International Polymer Conference (IPC2012). The presentation title is "Improved stability of PICsomes (polyion complex vesicles) against environmental changes by introducing guanidinium moieties in polycation segment" (coauthers：Y. Anraku, A. Kishimura and K. Kataoka).
12.10
Professor Kazunori Kataoka’s work on polymeric micelles has been highlighted in Nature Outlook “Nanotechnology: Carrying drugs”. The importance of the size of nanomedicines was illustrated with a picture from our recent publication in Nature Nanotechnology, “Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size”.
11.26
Assistant Professor Kanjiro Miyata received The Award for Young Investigator of Japanese Society for Biomaterials (2012). The award-winning research title is "Fine-tuning of polymeric nanomaterials for enhanced nucleic acid delivery with lower cytotoxicity".
11.26
Dr. Satoshi Uchida received the Best Poster Award at Symposium 2012 of the Japanese Society for Biomaterials. His presentation title is "Development and functional analyses of nonviral carriers for in vivo mRNA delivery" (coauthers: Keiji Itaka, Kazunori Kataoka).
10.30
Assistant Professor Kanjiro Miyata received Award for Encouragement of Research in Materials Science; The Materials Research Society of Japan in IUMRS-ICEM 2012 (Sep/27/2012). The presentation title is "Smart Multilayered Polymer/Silica Assemblies for Enhanced siRNA Delivery" (coauthors: T. Suma, S. Watanabe, Y. Anraku, N. Gouda, T. Takemoto, T. Ishii, A. Kishimura, N. Nishiyama, K. Kataoka).
10.22
Our paper entitled "A Phenylboronate-Functionalized Polyion Complex Micelle for ATP-Triggered Release of siRNA" has been published on Angewandte Chemie (Volume 51, Issue 43, 10751-10755, 2012) and selected as a cover.(Cover・Paper)
10.22
Prof. Kataoka becomes President of Controlled Release Society, the leading International Society in drug delivery field.
10.22
Professor Kazunori Kataoka attended the Leo Esaki Prize ceremony.
09.18
Nano-Bio FIRST symposium will hold on October 5.
09.01
Research achievements of Prof. Kazunori Kataoka was carried on the column of Yomiuri Newspaper.
08.29
Dr. Kensuke Osada (Associate Professor) was selected as PRESTO (Precursory Research for Embryonic Science and Technology) researcher in the project of Molecular technology and creation of new functions.
08.18
Our paper entitled "Accelerated Polymer-Polymer Click Conjugation by Freeze-Thaw Treatment" has been published on Bioconjugate Chemistry (Volume 23, Issue 8, 1503-1506, 2012) and selected as a cover. (Cover・Paper)
08.10
Mr. Kazuya Nagata (D1) awarded Yao Su student research award at the summer students seminar of Massachusetts General Hospital. His awarded research topic is "Low Level Laser Therapy protects primary cortical neurons from excitotoxicity"（coauthors:Ying-ying Huang, Michael R. Hamblin).
07.25
Professor Kazunori Kataoka awarded the 2012 Leo Esaki Prize. Awards ceremony will be held on October, 2012 in Tsukuba, Japan.
07.05
Dr. Satoshi Uchida (D4) received the Best Presentation Award at the 28th Japan DDS Conference. His presentation title is " In vivo mRNA delivery to central nervous system using polyplex nanomicelles" (coauthors: Kentaro Hayakawa, Toru Ogata, Keiji Itaka, Kazunori Kataoka).
07.05
Mr. Takahiro Nomoto (D2) received the Best Presentation Award at the 28th Japan DDS Conference. His presentation title is "Quantitative evaluation of dynamic states of polyion complexes in bloodstream using intravital real-time confocal laser scanning microscopy" (coauthors: Yu Matsumoto, Kanjiro Miyata, Makoto Oba, Shigeto Fukushima, Nobuhiro Nishiyama, Kazunori Kataoka).
06.08
Associate Professor Nobuhiro Nishiyama received Japanese Cancer Association Young Investigator Award. His presentation title is "Development of Polymeric Micelles as Drug Delivery System for Targeted Therapy of Intractable Cancers".
06.05
Mr. Peng Mi (D3) received Young Scientist Award at the 9th World Biomaterials Congress (WBC) for the oral presentation session. His presentation title is “Gd-DTPA loaded polymeric micelle with high relaxivity for in vivo cancer diagnosis” (coauthors: Horacio Cabral, Sachiko Kaida, Daisuke Kokuryo, Nobuhiro Nishiyama, Ichio Aoki and Kazunori Kataoka).
06.02
Professor Kazunori Kataoka was conferred the Honorary Professorship from Sichuan University, China.
05.09
Dr. Hirokuni Uchida received 2nd prize at Johnson & Johnson Services, Inc (“JJSI”) Asia Outstanding Graduate Thesis Award in Bio-tech. His presentation title is "Effect of Repeating Aminoethylene Units in the Side Chain of N-Substituted Polyaspartamides on Gene Transfection Profiles".
03.23
Professor Kazunori Kataoka attended the Humboldt Research Awards ceremony.
03.22
Our paper entitled "Rational design of smart supramolecular assemblies for gene delivery: chemical challenges in the creation of artificial viruses" has been published on Chemical Society Reviews (Volume 41, Issue 7, 7 April 2012) and selected as an inside cover. (Paper, Inside front cover)
02.16
Newsletters of NanoBio FIRST are now ready for downloading at the FIRST program website provided by Japan Science and Technology Agency (JST).
01.25
Professor Kazunori Kataoka awarded the Humboldt Research Award (Awards ceremony to be held on March 23, 2012).
01.23
Our collaboration work regarding controlled insulin release using synthetic polymer gel has been published on Angew. Chem. In. Ed. and selected as an inside cover.
01.20
Dr. Yu Matsumoto received the Konica Minolta Imaging Science Award 2012. His title is "Intravital Real-Time Confocal Laser Scanning Microscopy for In Situ Evaluation of Drug Delivery Systems".
01.10
Dr. Yasutaka Anraku received the Takagi award at the 21th Inteligent Materials/Systems Symposium. His presentation title is "Development of nano-sized polyion complex polymersome (Nano-PICsomes) for a versatile DDS carrier" (coauthors: Akihiro Kishimura, Kazunori Kataoka).
11.25
Dr. Hitomi Hiruma received the meeting award 2011 at the 32th Congress of Japan Society for Laser Surgery and Medicine (JSLSM). The presentation title is "Validation of PDD and PDT effect of dendrimer porphyrin micelle".
11.24
Associate Professor Keiji Itaka received The Award for Young Investigator of Japanese Society for Biomaterials 2011. The presentation title is "Development of biocompatible nanocarrier for gene delivery and its application for disease treatment".
10.24
Our paper entitled "Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size" was published in Nature Nanotechnology (Published online: 23 October 2011; doi:10.1038/nnano.2011.166) and the research of the paper was carried in Mainichi Newspaper, Sankei Newspaper, Yomiuri Newspaper etc.
10.03
Ms. Huailiang Wu received the Best Presentation Award at the Retreat 2011 (The University of Tokyo Global COE: Center for Medical System Innovation). The presentation title is "Targeting Metastatic Events with Polymeric Micelles".
09.12
Dr. Yasutaka Anraku received the Best Poster Presentation Award at the 63th Divisional Meeting on Colloid and Interface Chemistry. The presentation title is "Development of nano-sized polyion complex polymersome (Nano-PICsomes) for intelligent DDS carrier" (coauthors: Akihiro Kishimura, Kazunori Kataoka).
06.10
Dr. Miyuki Baba received the Best Presentation Award at the 27th Japan DDS Conference. Her presentation title is "Reducing the Ototoxic Effect of Cisplatin by Micellization" (coauthors: Yu Matsumoto, Horacio Cabral, Nobuhiro Nishiyama, Kazunori Kataoka, Tatsuya Yamasoba).
04.30
Our paper entitled "In situ quantitative monitoring of polyplexes and polyplex micelles in the blood circulation using intravital real-time confocal laser scanning microscopy" was selected as a cover of Journal of Controlled Release (Volume 151, Issue 2, 30 April 2011). This study was further featured as a cover story.
04.15
Dr. Yu Matsumoto received 5th Panel Exhibition of 'Beauty' in Science Technology, Award for Exellence. His presentation title is "Tumor Drug Delivery".
03.01
Assistant Professor Kishimura received Award for Encouragement of Research in Polymer Science; The Society of Polymer Science, Japan (2010). His research title is "Development of polyion-complex vesicles based on water-soluble block copolymers toward biomedical applications".
02.23
Mr. Takemoto's paper (Biomaterials) was selected as "The new Biomaterials Year in Images poster - 2010 edition". The title is "Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system.".
02.10
Polymeric micelles as nano-scaled Trojan Horse was highlighted in the web site of Nature Japan for the successful chemotherapy to treat drug-resistant tumors.
01.28
Targeting therapy to treat drug-resistant tumor by polymeric micelles were carried in Nikkei Sangyo Shimbun.
01.24
Our research "Drug Delivery System overcomes the acquired drug resistance in cancer cells"(The pdf file is available from here) was carried in TV program by NHK.
01.06
Our paper entitled "Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting" was selected as a cover of Sci. Transl. Med.(Vol.3, No.64, January 2011) (PDF, Cover Image) and the research of the paper was carried in Nippon Keizai Newspaper, Mainichi Newspaper, Yomiuri Newspaper, NHK News etc.
01.06
Assistant Professor Kishimura received the Takagi award at the 20th Inteligent Materials/Systems Symposium. His presentation title is "Development of polyion complex nano-vesicles "PICsomes" toward novel intelligent DDS" (coauthors: Yasutaka Anraku, Stephanie Lee, Sayan Chuanoi, Kanjiro Miyata, Kazunori Kataoka).
12.16
Targeting therapy of cancer by polymeric micelles was carried in Yomiuri Shimbun.
10.04
Research activity of Kataoka Lab was carried in September 2010 issue of "Highlighting Japan" published by the Japanese Government.
09.27
The first University of Tokyo Autumn Graduation Ceremony was held. Representative of the graduating students, Ms. Yelena Vachutinsky made an address in reply to President Hamada's address. (Detail, Photo, Speech)
09.21
Author profile of Prof. Kazunori Kataoka has been highlighted in Angewandte Chemie, International Edition 49(31), 5218 (2010).
09.09
Development of visible drug delivery system for the diagnosis and therapy of pancreatic tumors was carried in Mainichi Newspaper, Nikkei Sangyo Newspaper, Nippon Keizai Newspaper (Web) and Kagaku Shimbun(Oct.1) (Professor Kazunori Kataoka / Professor Toru Tani, Department of Surgery, Shiga University of Medical Science / Dr. Ichio Aoki, Molecular Imaging Center, National Institute of Radiological Sciences). This study was featured as the sidebar cover in September 15th issue of Cancer Research, an official journal of the American Association of Cancer Research.
09.02
Dr. Cristina Garmendia, the Minister of Science Innovation, Spain, and her delegates visited our laboratory to inspect our FIRST project on nanobiotechnolgy and drug delivery.
07.13
Targeting therapy of cancer by self-assembled nanocarriers was carried in Nikkei Sangyo Shimbun.
07.01
Our paper entitled " pDNA/poly(L-lysine) polyplexes functionalized with a pH-sensitive charge-conversional poly(aspartamide) derivative for controlled gene delivery to human umbilical vein endothelial cells " was selected as a cover of Macroml. Rapid Commun..
06.29
Our recent paper entitled "Assessment of Tumor Metastasis by the Direct Determination of Cell Membrane Sialic Acid Expression" in collaboration with Prof. A. Matsumoto (Department of Bioengineering) and Prof. Y.Miyahara (Director, Biomaterials Centre, National Institute for Materials Science) was selected as a "Hot Paper" in Angew. Chem. Int. Ed.
05.27
Professor Kataoka was inaugurated as 30th President of the Society of Polymer Science, Japan.
05.25
Professor Kataoka was elected to the Vice President of Controlled Release Society.
05.13
Versatile and selective synthesis of "Click Chemistry" compatible heterobifunctional poly(ethylene glycol)s possessing azide and alkyne functionalities. Bioconjugate. Chem. 21 (2) 248-254 (2010) DOI: 10.1021/bc900253p was selected as the ten most-accessed articles from Bioconjugate Chemistry during the first quarter of 2010. (Details)
05.11
Assistant Professor Miyata received Award for Encouragement of Research in Polymer Science; The Society of Polymer Science, Japan (2009). His research title is "Development of Cationic Poly(amino acid)s for Safe and Efficient Nucleic Acids Delivery".
05.06
Professor Kataoka was elected as a Fellow of the inaugural College of Fellows of the Controlled Release Society.
04.09
Project Researcher. Matsumoto's pictures taken through the research were nominated as 'The Beauty of Science' panel exhibition during 'Science Technology Week' held by MEXT (Ministry of Education, Culture, Sports, Science and Technology).
04.05
Prize for Science and Technology, The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology was given to Prof. Kataoka.
03.30
Research on intracellular antibody delivery (Angew. Chem. Int'l Ed, 49(10) 2552-2555 (2010)) was highlighted in Science-Business eXchange (SciBX) Journal published by Nature Publishing Co.
03.16
Development of novel siRNA delivery system for the treatment of kidney diseases was carried in Nippon Keizai Shimbun and Asahi Shimbun (Professor Kazunori Kataoka, Graduate Schools of Engineering and Medicine, Professor Toshiro Fujita, University of Tokyo Hospital). (Details)
02.23
The history of cisplatin-incorporated polymeric micelles, which were originally developed by Dr. Nishiyama and have progressed to clinical trials, was carried in Mainich Newspaper. This paper also describes the future prospects for DDS.
12.08
Assistant Professor Kishimura received the best presentation award at the 18th Polymer Material Forum. His presentation title is "Development of Polyion complex vesicles 'Nano-PICsomes' with tunable size and stability in submicron region.".
12.02
Assistant Professor Miyazaki received the meeting award 2009 at the 30th Congress of Japan Society for Laser Surgery and Medicine (JSLSM). His presentation title is "Enhanced effects of PDT by the use of a fiber probe with a newly developed diffuser tip".
10.26
Assistant professor Kishimura was selected as a speaker of Young Scholar Lecture Series of The Chemical Society of Japan for 2010.
07.15
Our paper was selected as a cover of Angew. Chem. Int. Ed.. (Detail)
07.03
Assistant Professor Miyata received the Best Poster Award at 25th JAPAN DDS Conference. His presentation title is "Design of polymeric gene carriers possessing efficient endosomal escape with negligible cytotoxicity and their application for systemic gene delivery".
07.02
Associate Professor Nishiyama received "Young Investigator's award" from The Japan Sciety of Drug Delivery System.
07.01
Our paper entitled "Nanopolymeric Therapeutics" was selected as a cover of MRS Bulletin.
06.29
Professor Kataoka received received "NIMS Award 2009" from National Institute for Materials Science. The award title is "Development of Functional Nanodevices for Drug and Gene Delivery".
05.11
Polymeric micellar drug carriers developed by our laboratory was carried in NIkkei Newspaper. Overview: Direct targeting of cancer by DDS - Micellar nanocarriers developed by the group of Prof. Kataoka has successfully been in clinical trial in Japan and USA, revealing their promising system to treat intractable cancers. Novel nanocarriers modulating drug action by external energy, including light, has also been developed in his group, and are expected to be the most promising system in nanomedicine for cancer treatment. (May 10, 2009)
05.07
Our paper entitled "Spontaneous formation of giant unilamellar vesicles from microdroplets of a polyion complex by thermally induced phase separation", which is collaboration work with Prof. H. Oana (Department of Mechanical Engineering), was selected as a "Hot Paper" in Angew. Chem. Int. Ed.
04.21
Novel nanocarriers delivering various protein molecules into cytoplasm has been developed by Dr. Yan Lee (Assistant Professor) and colleagues. Proteins with diverse molecular weights, including antibodies, were successfully delivered into cytoplasm with maintaining their original activities. This method is expected to be applied for diagnosis and therapy of various diseases including cancer (Nikkei Business Daily / The Chemical Daily, March 24, 2009/Mainichi Daily News, April 21, 2009).
03.25
Novel nanocarriers delivering various protein molecules into cytoplasm has been developed by Dr. Yan Lee (Assistant Professor) and colleagues. Proteins with diverse molecular weights, including antibodies, were successfully delivered into cytoplasm with maintaining their original activities. This method is expected to be applied for diagnosis and therapy of various diseases including cancer (Nikkei Business Daily / The Chemical Daily, March 24, 2009).
03.10
Our paper entitled "Design and development of dendrimer photosensitizer-incorporated polymeric micelles for enhanced photodynamic therapy" was selected as a cover of Advanced Drug Delivery Reviews.
02.16
Our paper entitled "Enhanced photodynamic cancer treatment by supramolecular nanocarriers charged with dendrimer phthalocyanine" was selected as a cover of Journal of Controlled Release (Vol. 133, No.3) published in February 2009.
02.03
Ms. Mai Sanjoh (D2) received the progressive award at the Teijin 21st Century Forum. The presentation title is "New Design and Evaluation of Charge-Conversion poly(amino acid) For effective gene delivery".
01.29
Confocal fluorescence images of "Intracellular distribution of polymeric micelles loading plasmid DNA" of this laboratory made a cover of the Journal "Pharmaceutical Research Vol. 25 No. 12" published in December, 2008.
11.27
Dachplatin-loaded polymeric micelle developed in this laboratory will proceed into phase I clinical trial in Europe by NanoCarrier Co. and Debio Pharm Co. (Prof. Kazunori Kataoka)
11.27
Dr. Kanjiro Miyata (Project Assistant Professor) received the Best Poster Award at NanoBio-Seoul 2008. His presentation title is "Triblock Copolymer Micelles Bearing Biocompatible, Endosomal Escaping, DNA-Condensing Abilities for Systemic Gene Delivery".
11.11
Prof. Kataoka received Special Prize on Cooperative Manufacturing Award from Business & Technology Deily News for the topic on "intelligent nano-particle".
07.28
CNBI/CNSI Joint Symposium on NanoBio will be held at University of Tokyo on September 8th & 9th, 2008. (Detail).
07.24
Professor Kataoka received Founders Award from Controlled Release Society, the largest International Society in the filed of drug delivery
05.19
"Water-Soluble Polyion Complex Associates of DNA and Poly(ethylene glycol)-Poly(L-lysine) Block Copolymer" published in Bioconjugate Chemistry from this laboratory is being featured on the ACS Publications website as a Most-Cited Article as of March 31st, 2008.
05.19
Mr. Hirokuni Uchida (M2) received the Encouragement Award for Poster Presentation at 8th Symposium of Japanese Society for Gene Design & Delivery. His presentation title is "Construction and Evaluation of Novel Gene Vector from Polyaspartamide Derivatives Having Various Cationic Side Groups".
05.12
Mr. Yasutaka Anraku (D2) received the CSJ Student Presentation Award 2008. His presentation title is “Development of Nano-sized PICsomes and Evaluation of Their Properties”.
01.21
Mr. Daigo Kobayashi (graduate student) received the Best Poster Award at the 19th Annual Symposium of the Research group on Polymer Gels. His presentation title is “Difference on preparation in plasmid DNA condensation induced by PEG-PLys block copolymer, titration or one shot mixing.
12.28
Dr. Akihiro Kishimura (Assistant Professor) received the 24th Inoue Research Award for Young Scientists from Inoue Foundation for Science.
11.05
Novel DDS technology (DachPlatin-loaded polymeric micelle) developed in Kataoka lab has been licensed to DebioPharm (Switzerland) Co. through NanoCarrier Co. for clinical development.
07.27
Invention on nobel micellar-type aniti-cancer drug (Dachplatin-micelle) has patented, and will proceed into clinical trial by Nanocarrier Co.
07.24
Research achievements of our lab "Nanocapsule for drug delivery" has been broadcasted from Science Channel.
06.18
Dr. Makoto Oba (Assistant Professor) received Best Poster Award at The 23rd Annual Conference of The Japan Drug Delivery System Society.His presentation title is "Development of polymeric micellar type gene vector with cyclic RGD ligand and SS-crosslinked core".
06.18
NIKKEI SANGYO paper has carried The University of Tokyo Center for NanoBio Integration (June, 12-13, 2007). Professor Kataoka is the Center Director.
04.09
Our recent results on the accumulation of polymeric micelles into intractable cancer (collaborative research with Prof. K. Miyazono, Medical School, The University of Tokyo) was introduces as the Research Highlights of Nature Reviews Drug Discovery.
04.04
Our recent results on photochemical transfection was highlighted in the commentary of the recent issue of Nature Materials (Vol.6, 251-253 (2007)).
02.19
New concept for the delivery of polymeric micelles to hypovascular pancreatic cancer was developed by our group, and the results were published in Proc. Nat'l. Acad. Sci., USA. This work was done in collaboration with Prof. Kohei Miyazono and Dr. Mitsunobu R. Kano, Graduate School of Medicine, The University of Tokyo
01.23
YOMIURI News Paper has carried the story on the development of polymeric micellar nanocarrier (January 22, 2007)
01.02
"Polyion Complex Micelles with a Novel Thermosensitive Poly(2-isopropyl-2-oxazoline) Shell" of K.K.Lab made a cover of the Journal “Langmuir” Published in January 2, 2007.
11.10
Our paper "Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery, Mol. BioSyst. 1, 242 (2005)" is listed on Top 2 most accessed paper of the journal "Molecuar BioSystms" published by Royal Society of Chemistry.
10.16
Professor Kataoka received Latta Lectureship from University of Nebraska Medical Center, Alumni Association, USA.
10.02
NIKKEI news paper has carried out our recent research on polymeric micelle for cancer chemotherapy to be proceeded into clinical trials in Japan and England.
09.20
Professor Kataoka received Barre Award from University of Montreal, Canada. (Photo1, Photo2)
07.11
NIKKEI SANGYO news paper has carried our recent research using DDS (July, 07. 2006)
06.29
Our article "Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery" was amongst the top 20 most accessed on the web version of Molecular BioSystems during its first year of publication.
03.01
An interview article was carried by an official bulletin of department of engineering, the University of Tokyo.
01.29
Our research team won the poster prize in the Teijin group-sponsored Fujisusono 21st century forum.
01.24
Professor Kataoka was chosen as one of the "100 Most-Cited Scientists in Pharmacology & Toxicology".(details)
12.01
The new projcet "Center for NanoBio Integration(CNBI)" has been set forward to projecticle advanced research and developement of nanotechnology, which is supported by Ministry of Education, Culuture, Sports, Science and Technology(MEXT).
11.29
Our latest research on intelligent nanobiomachines for the optical remote controlled gene transfection has been published in Nature Materials. This research is performed through collaboration by members of Department of Ophthalmology, The University of Tokyo Hospital, and it is an epoch-making technology that facilitates pinpoint gene expression at the targeted site in the body. Please read the full article for more about details, as well as click links to view news items carried by the Yomiuri Newspaper, the Asahi Newspaper, Nihon Keizai Newspaper, and Kyodo News.
10.31
Our recently developed polymeric micellar gene vectors have successfully achieved gene expression in liver through intravenously injection followed by systemic gene delivery. (Oct. 31, 2005, Nikkei-Sangyo simbun)
10.27
Light-sensitive polymeric micellar nano machine has been reported by Nano Letters. You can also see details on the website, nanotechweb
08.29
The Cooperative Unit of Medicine and Engineering Research has started at the University of Tokyo Hospital. And its website goes online. (click here to Cooperative Unit of Kataoka Laboratory and Department of Vascular Regeneration)
08.22
Our "Targeted pH Sensitive Nanoparticle Releases Drug Inside Tumor Cells " was reported in the Hot topics of Nanotech News section of National Cancer Institute, USA. (Detail)
04.25
Our "DACHPt-loaded micelle study" goes to clinical development supported by the Japanese company, NanoCarrier, and the Swiss firm, Debiopharm.(Detail)
04.01
New webpage from CREST is open! Link (What's CREST?)
03.14
Original Papers" update in the Publications section
11.22
Our study is published in "The second annual symposium on nanomedicine and drug delivery-Meeting Highlights".
11.22
"Dendrimer study"; the joint research of this Kataoka Lab and Aida Lab( Department of Chemical and Biotechnology school of Engineering, The University of Tokyo) appeared in the 30/10/2004 issue of Asahi newspaper.
11.14
"Recent Deployment of Drug Delivery System - aiming at ultimate drug therapy(Japanese only)" has published (Prof. Kataoka is one of the authors).
10.23
"Nano Bioengineering Education Program" (rep:Prof. Kataoka) newly starts ( English version is coming soon!)
10.11
"Zero in on the cancer cells and destroy them" appeared in the 24/09/2004 issue of Nikkei newspaper .
09.09
"Polymer Micelle" of K.K.Lab appeared in the October issue of NikkeiScience Magazine.
07.25
Prof.Kataoka holds the post of both technology faculty and medical faculty. Link(Japanese only)
07.03
Prof.Kataoka got the plaque from Prof. James M. Anderson(Society President) in honor of charing the 31st Annual Meeting and Exposition of the Controlled Release Society (Honolulu, June 12-16, 2004).
06.25
Hepatocyte heterospheroids Array" of K.K.Lab made the cover of the Journal "ChEM BIO CHEm" published in published in 2004
05.02
Bionanoreactor Protein Carrier System" of K.K.Lab made the cover of the Journal "BioConjugate Chemistry" published in April,2004.
01.04
Polymer Micelle" was adopted as the design of a postal stamp.([1] [2])